Literature DB >> 25473056

GB virus C coinfections in west African Ebola patients.

Michael Lauck1, Adam L Bailey1, Kristian G Andersen2, Tony L Goldberg3, Pardis C Sabeti2, David H O'Connor4.   

Abstract

In 49 patients with known Ebola virus disease outcomes during the ongoing outbreak in Sierra Leone, 13 were coinfected with the immunomodulatory pegivirus GB virus C (GBV-C). Fifty-three percent of these GBV-C(+) patients survived; in contrast, only 22% of GBV-C(-) patients survived. Both survival and GBV-C status were associated with age, with older patients having lower survival rates and intermediate-age patients (21 to 45 years) having the highest rate of GBV-C infection. Understanding the separate and combined effects of GBV-C and age on Ebola virus survival may lead to new treatment and prevention strategies, perhaps through age-related pathways of immune activation.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2014        PMID： 25473056      PMCID： PMC4338908          DOI： 10.1128/JVI.02752-14

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  43 in total

1.  GBV-C/HGV genotypes: proposed nomenclature for genotypes 1-5.

Authors:  T J Tucker; H E Smuts
Journal:  J Med Virol       Date:  2000-09       Impact factor: 2.327

2.  Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily.

Authors:  Lisa E Hensley; Howard A Young; Peter B Jahrling; Thomas W Geisbert
Journal:  Immunol Lett       Date:  2002-03-01       Impact factor: 3.685

3.  Inflammatory responses in Ebola virus-infected patients.

Authors:  S Baize; E M Leroy; A J Georges; M-C Georges-Courbot; M Capron; I Bedjabaga; J Lansoud-Soukate; E Mavoungou
Journal:  Clin Exp Immunol       Date:  2002-04       Impact factor: 4.330

4.  Effect of coinfection with GB virus C on survival among patients with HIV infection.

Authors:  J Xiang; S Wünschmann; D J Diekema; D Klinzman; K D Patrick; S L George; J T Stapleton
Journal:  N Engl J Med       Date:  2001-09-06       Impact factor: 91.245

5.  Infection with GB virus C and reduced mortality among HIV-infected patients.

Authors:  H L Tillmann; H Heiken; A Knapik-Botor; S Heringlake; J Ockenga; J C Wilber; B Goergen; J Detmer; M McMorrow; M Stoll; R E Schmidt; M P Manns
Journal:  N Engl J Med       Date:  2001-09-06       Impact factor: 91.245

6.  Clinical illness and outcomes in patients with Ebola in Sierra Leone.

Authors:  John S Schieffelin; Jeffrey G Shaffer; Augustine Goba; Michael Gbakie; Stephen K Gire; Andres Colubri; Rachel S G Sealfon; Lansana Kanneh; Alex Moigboi; Mambu Momoh; Mohammed Fullah; Lina M Moses; Bethany L Brown; Kristian G Andersen; Sarah Winnicki; Stephen F Schaffner; Daniel J Park; Nathan L Yozwiak; Pan-Pan Jiang; David Kargbo; Simbirie Jalloh; Mbalu Fonnie; Vandi Sinnah; Issa French; Alice Kovoma; Fatima K Kamara; Veronica Tucker; Edwin Konuwa; Josephine Sellu; Ibrahim Mustapha; Momoh Foday; Mohamed Yillah; Franklyn Kanneh; Sidiki Saffa; James L B Massally; Matt L Boisen; Luis M Branco; Mohamed A Vandi; Donald S Grant; Christian Happi; Sahr M Gevao; Thomas E Fletcher; Robert A Fowler; Daniel G Bausch; Pardis C Sabeti; S Humarr Khan; Robert F Garry
Journal:  N Engl J Med       Date:  2014-10-29       Impact factor: 91.245

7.  Pathogenesis of Ebola hemorrhagic fever in primate models: evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells.

Authors:  Thomas W Geisbert; Howard A Young; Peter B Jahrling; Kelly J Davis; Tom Larsen; Elliott Kagan; Lisa E Hensley
Journal:  Am J Pathol       Date:  2003-12       Impact factor: 4.307

8.  Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection.

Authors:  Thomas W Geisbert; Lisa E Hensley; Tom Larsen; Howard A Young; Douglas S Reed; Joan B Geisbert; Dana P Scott; Elliott Kagan; Peter B Jahrling; Kelly J Davis
Journal:  Am J Pathol       Date:  2003-12       Impact factor: 4.307

9.  Persistent GB virus C infection and survival in HIV-infected men.

Authors:  Carolyn F Williams; Donna Klinzman; Traci E Yamashita; Jinhua Xiang; Philip M Polgreen; Charles Rinaldo; Chenglong Liu; John Phair; Joseph B Margolick; Dietmar Zdunek; Georg Hess; Jack T Stapleton
Journal:  N Engl J Med       Date:  2004-03-04       Impact factor: 91.245

10.  Regulation of CC chemokine receptor 5 in hepatitis G virus infection.

Authors:  Jacob Nattermann; Hans-Dieter Nischalke; Bernd Kupfer; Jürgen Rockstroh; Lothar Hess; Tilman Sauerbruch; Ulrich Spengler
Journal:  AIDS       Date:  2003-07-04       Impact factor: 4.177
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  30 in total

Review 1.  Tropism of human pegivirus (formerly known as GB virus C/hepatitis G virus) and host immunomodulation: insights into a highly successful viral infection.

Authors:  Ernest T Chivero; Jack T Stapleton
Journal:  J Gen Virol       Date:  2015-02-09       Impact factor: 3.891

2.  Ebola and pregnancy.

Authors:  Viroj Wiwanitkit
Journal:  Obstet Med       Date:  2016-03-11

3.  [Detection of a novel human pegivirus HPgV-2 in healthy blood donors and recipients of multiple transfusions: implications for blood safety].

Authors:  Naling Zhu; Ru Xu; Weiping Tang; Haiying Wang; Zhengwei Wan; Xuedong Wu; Yongshui Fu; Shixing Tang; Shouyi Yu
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2018-07-30

4.  Human pegivirus 1 in Cabo Verde: prevalence and genotypic distribution among HIV-infected individuals.

Authors:  Isabel Inês M de Pina-Araujo; Marco Aurélio Horta; Francisco Campello do Amaral Mello; Caroline Cordeiro Soares
Journal:  Arch Virol       Date:  2021-03-10       Impact factor: 2.574

5.  Durable sequence stability and bone marrow tropism in a macaque model of human pegivirus infection.

Authors:  Adam L Bailey; Michael Lauck; Mariel Mohns; Eric J Peterson; Kerry Beheler; Kevin G Brunner; Kristin Crosno; Andres Mejia; James Mutschler; Matthew Gehrke; Justin Greene; Adam J Ericsen; Andrea Weiler; Gabrielle Lehrer-Brey; Thomas C Friedrich; Samuel D Sibley; Esper G Kallas; Saverio Capuano; Jeffrey Rogers; Tony L Goldberg; Heather A Simmons; David H O'Connor
Journal:  Sci Transl Med       Date:  2015-09-16       Impact factor: 17.956

6.  Plasmodium Parasitemia Associated With Increased Survival in Ebola Virus-Infected Patients.

Authors:  Kyle Rosenke; Jennifer Adjemian; Vincent J Munster; Andrea Marzi; Darryl Falzarano; Clayton O Onyango; Melvin Ochieng; Bonventure Juma; Robert J Fischer; Joseph B Prescott; David Safronetz; Victor Omballa; Collins Owuor; Thomas Hoenen; Allison Groseth; Cynthia Martellaro; Neeltje van Doremalen; Galina Zemtsova; Joshua Self; Trenton Bushmaker; Kristin McNally; Thomas Rowe; Shannon L Emery; Friederike Feldmann; Brandi N Williamson; Sonja M Best; Tolbert G Nyenswah; Allen Grolla; James E Strong; Gary Kobinger; Fatorma K Bolay; Kathryn C Zoon; Jorgen Stassijns; Ruggero Giuliani; Martin de Smet; Stuart T Nichol; Barry Fields; Armand Sprecher; Moses Massaquoi; Heinz Feldmann; Emmie de Wit
Journal:  Clin Infect Dis       Date:  2016-08-15       Impact factor: 9.079

7.  Arteriviruses, Pegiviruses, and Lentiviruses Are Common among Wild African Monkeys.

Authors:  Adam L Bailey; Michael Lauck; Ria R Ghai; Chase W Nelson; Katelyn Heimbruch; Austin L Hughes; Tony L Goldberg; Jens H Kuhn; Anna J Jasinska; Nelson B Freimer; Cristian Apetrei; David H O'Connor
Journal:  J Virol       Date:  2016-07-11       Impact factor: 5.103

Review 8.  Surveying the global virome: identification and characterization of HCV-related animal hepaciviruses.

Authors:  Troels K H Scheel; Peter Simmonds; Amit Kapoor
Journal:  Antiviral Res       Date:  2014-12-26       Impact factor: 5.970

9.  Human Pegivirus (HPgV; formerly known as GBV-C) inhibits IL-12 dependent natural killer cell function.

Authors:  Ernest T Chivero; Nirjal Bhattarai; James H McLinden; Jinhua Xiang; Jack T Stapleton
Journal:  Virology       Date:  2015-08-01       Impact factor: 3.616

10.  Discovery of a Novel Human Pegivirus in Blood Associated with Hepatitis C Virus Co-Infection.

Authors:  Michael G Berg; Deanna Lee; Kelly Coller; Matthew Frankel; Andrew Aronsohn; Kevin Cheng; Kenn Forberg; Marilee Marcinkus; Samia N Naccache; George Dawson; Catherine Brennan; Donald M Jensen; John Hackett; Charles Y Chiu
Journal:  PLoS Pathog       Date:  2015-12-11       Impact factor: 6.823
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