Literature DB >> 2547259

The molecular biology of hepatitis B virus.

H E Blum, W Gerok, G N Vyas.   

Abstract

Infection with the hepatitis B virus (HBV) or related hepadnaviruses is associated with a wide spectrum of liver diseases, including hepatocellular carcinoma (HCC). In this article we review the current state of knowledge about the structure, genetic organization and life cycle of HBV. The mechanisms of viral pathogenesis and HCC development remain poorly understood, but new approaches may soon begin to shed light on these areas.

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Year:  1989        PMID： 2547259     DOI： 10.1016/0168-9525(89)90057-7

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  11 in total

1.  Some factors influencing the proportion of periplasmic hepatitis B virus pre-S2 antigen in the recombinant yeast Hansenula polymorpha.

Authors:  M R de Roubin; M D Cailas; S H Shen; D Groleau
Journal:  J Ind Microbiol       Date:  1992-01

Review 2.  [Hepatology. New research results in its significance for the understanding of liver diseases].

Authors:  W Gerok; H E Blum; W Offensperger; S Offensperger; T Andus; V Gross; P C Heinrich
Journal:  Naturwissenschaften       Date:  1991-06

3.  The ubiquitous transcription factor Oct-1 and the liver-specific factor HNF-1 are both required to activate transcription of a hepatitis B virus promoter.

Authors:  D X Zhou; T S Yen
Journal:  Mol Cell Biol       Date:  1991-03       Impact factor: 4.272

Review 4.  New therapeutic vaccination strategies for the treatment of chronic hepatitis B.

Authors:  Jia Liu; Anna Kosinska; Mengji Lu; Michael Roggendorf
Journal:  Virol Sin       Date:  2014-01-17       Impact factor: 4.327

5.  Duck hepatitis B virus polymerase acts as a suppressor of core protein translation.

Authors:  A Y Howe; D L Tyrrell
Journal:  J Virol       Date:  1996-08       Impact factor: 5.103

6.  BAP, a rat liver protein that activates transcription through a promoter element with similarity to the USF/MLTF binding site.

Authors:  W Kugler; M Kaling; K Ross; U Wagner; G U Ryffel
Journal:  Nucleic Acids Res       Date:  1990-12-11       Impact factor: 16.971

7.  Therapeutic advances in the management of chronic hepatitis B infection.

Authors:  Johanne Brooks; William Gelson; Simon M Rushbrook
Journal:  Ther Adv Chronic Dis       Date:  2013-07       Impact factor: 5.091

8.  Identification and cloning of a novel heterogeneous nuclear ribonucleoprotein C-like protein that functions as a transcriptional activator of the hepatitis B virus enhancer II.

Authors:  N Tay; S H Chan; E C Ren
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103

9.  Aberrant tissue specific expression of the transgene in transgenic mice that carry the hepatitis B virus genome defective in the X gene.

Authors:  H Nagashima; M Imai; Y Iwakura
Journal:  Arch Virol       Date:  1993       Impact factor: 2.574

Review 10.  Molecular hybridization techniques in current diagnosis of chronic hepatitis B in childhood.

Authors:  S Wirth; B Zabel
Journal:  Eur J Pediatr       Date:  1992-04       Impact factor: 3.183
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