CONTEXT: When evaluating bioactivity, efficacy, and toxicology of plant products, attention should be paid on pre-clinical versus clinical research. OBJECTIVE: To emphasize an evidence-based approach in the field of phytotherapy research. METHODS: The pyramid of scientific evidence was used in order to assess the quality of phytotherapy studies. RESULTS AND CONCLUSION: In terms of evidence-based phytotherapy, a step-by-step approach, ascending the "pyramid" of scientific evidence, is essential in order to collect correct information useful to clinicians and physicians, leant on the robust foundations of in vitro/in vivo studies.
CONTEXT: When evaluating bioactivity, efficacy, and toxicology of plant products, attention should be paid on pre-clinical versus clinical research. OBJECTIVE: To emphasize an evidence-based approach in the field of phytotherapy research. METHODS: The pyramid of scientific evidence was used in order to assess the quality of phytotherapy studies. RESULTS AND CONCLUSION: In terms of evidence-based phytotherapy, a step-by-step approach, ascending the "pyramid" of scientific evidence, is essential in order to collect correct information useful to clinicians and physicians, leant on the robust foundations of in vitro/in vivo studies.
Authors: Elena M Varoni; Rita Paroni; Jacopo Antognetti; Giovanni Lodi; Andrea Sardella; Antonio Carrassi; Marcello Iriti Journal: Molecules Date: 2018-09-27 Impact factor: 4.411