Literature DB >> 2547125

Recent developments in the design of receptor specific opioid peptides.

V J Hruby1, C A Gehrig.   

Abstract

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Year:  1989        PMID： 2547125     DOI： 10.1002/med.2610090306

Source DB:  PubMed          Journal:  Med Res Rev        ISSN： 0198-6325            Impact factor:   12.944


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  25 in total

1.  Biological and conformational evaluation of bifunctional compounds for opioid receptor agonists and neurokinin 1 receptor antagonists possessing two penicillamines.

Authors:  Takashi Yamamoto; Padma Nair; Neil E Jacobsen; Vinod Kulkarni; Peg Davis; Shou-Wu Ma; Edita Navratilova; Henry I Yamamura; Todd W Vanderah; Frank Porreca; Josephine Lai; Victor J Hruby
Journal:  J Med Chem       Date:  2010-08-12       Impact factor: 7.446

2.  New potent biphalin analogues containing p-fluoro-L-phenylalanine at the 4,4' positions and non-hydrazine linkers.

Authors:  Adriano Mollica; Francesco Pinnen; Federica Feliciani; Azzurra Stefanucci; Gino Lucente; Peg Davis; Frank Porreca; Shou-Wu Ma; Josephine Lai; Victor J Hruby
Journal:  Amino Acids       Date:  2010-10-06       Impact factor: 3.520

3.  The role of crystallography in drug design.

Authors:  Jeffrey R Deschamps
Journal:  AAPS J       Date:  2005-12-07       Impact factor: 4.009

4.  Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at mu and delta opioid receptors.

Authors:  Yeon Sun Lee; Joel Nyberg; Sharif Moye; Richard S Agnes; Peg Davis; Shou-wu Ma; Josephine Lai; Frank Porreca; Ruben Vardanyan; Victor J Hruby
Journal:  Bioorg Med Chem Lett       Date:  2007-02-08       Impact factor: 2.823

5.  Bifunctional [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues substituted at position 3 with alkylated phenylalanine derivatives yield potent mixed mu-agonist/delta-antagonist and dual mu-agonist/delta-agonist opioid ligands.

Authors:  Tingyou Li; Kimitaka Shiotani; Anna Miyazaki; Yuko Tsuda; Akihiro Ambo; Yusuke Sasaki; Yunden Jinsmaa; Ewa Marczak; Sharon D Bryant; Lawrence H Lazarus; Yoshio Okada
Journal:  J Med Chem       Date:  2007-05-12       Impact factor: 7.446

6.  Development of a common 3D pharmacophore for delta-opioid recognition from peptides and non-peptides using a novel computer program.

Authors:  P Huang; S Kim; G Loew
Journal:  J Comput Aided Mol Des       Date:  1997-01       Impact factor: 3.686

Review 7.  Design of peptide and peptidomimetic ligands with novel pharmacological activity profiles.

Authors:  Victor J Hruby; Minying Cai
Journal:  Annu Rev Pharmacol Toxicol       Date:  2013       Impact factor: 13.820

8.  Design and synthesis of opioidmimetics containing 2',6'-dimethyl-L-tyrosine and a pyrazinone-ring platform.

Authors:  Kimitaka Shiotani; Tingyou Li; Anna Miyazaki; Yuko Tsuda; Toshio Yokoi; Akihiro Ambo; Yusuke Sasaki; Sharon D Bryant; Lawrence H Lazarus; Yoshio Okada
Journal:  Bioorg Med Chem Lett       Date:  2007-08-28       Impact factor: 2.823

9.  Solid-phase synthetic strategy and bioevaluation of a labeled delta-opioid receptor ligand Dmt-Tic-Lys for in vivo imaging.

Authors:  Jatinder S Josan; David L Morse; Liping Xu; Maria Trissal; Brenda Baggett; Peg Davis; Josef Vagner; Robert J Gillies; Victor J Hruby
Journal:  Org Lett       Date:  2009-06-18       Impact factor: 6.005

10.  Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier.

Authors:  R Polt; F Porreca; L Z Szabò; E J Bilsky; P Davis; T J Abbruscato; T P Davis; R Harvath; H I Yamamura; V J Hruby
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-19       Impact factor: 11.205
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