Literature DB >> 25470540

Purloined mechanisms of bacterial immunity can cure muscular dystrophy.

James G Tidball1, Carmen Bertoni2.   

Abstract

Myriad strategies have been explored to compensate for the lack of dystrophin or to skip mutations that cause the lethal disease Duchenne muscular dystrophy (DMD). A new study shows that gene editing strategies used by bacteria can be applied in zygotes of a mouse model of DMD to correct the genetic defect that causes muscular dystrophy (Long et al., 2014).
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 25470540      PMCID: PMC4467519          DOI: 10.1016/j.cmet.2014.11.011

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  9 in total

1.  Early cleavage of in-vitro fertilized human embryos to the 2-cell stage: a novel indicator of embryo quality and viability.

Authors:  Y Shoukir; A Campana; T Farley; D Sakkas
Journal:  Hum Reprod       Date:  1997-07       Impact factor: 6.918

2.  Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA.

Authors:  Chengzu Long; John R McAnally; John M Shelton; Alex A Mireault; Rhonda Bassel-Duby; Eric N Olson
Journal:  Science       Date:  2014-08-14       Impact factor: 47.728

Review 3.  Development and applications of CRISPR-Cas9 for genome engineering.

Authors:  Patrick D Hsu; Eric S Lander; Feng Zhang
Journal:  Cell       Date:  2014-06-05       Impact factor: 41.582

4.  Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides.

Authors:  T A Rando; M H Disatnik; L Z Zhou
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-09       Impact factor: 11.205

5.  Site-directed gene repair of the dystrophin gene mediated by PNA-ssODNs.

Authors:  Refik Kayali; Frederic Bury; McIver Ballard; Carmen Bertoni
Journal:  Hum Mol Genet       Date:  2010-06-11       Impact factor: 6.150

6.  Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes.

Authors:  Shuo-Ting Yen; Min Zhang; Jian Min Deng; Shireen J Usman; Chad N Smith; Jan Parker-Thornburg; Paul G Swinton; James F Martin; Richard R Behringer
Journal:  Dev Biol       Date:  2014-06-28       Impact factor: 3.582

7.  Correction of a genetic disease in mouse via use of CRISPR-Cas9.

Authors:  Yuxuan Wu; Dan Liang; Yinghua Wang; Meizhu Bai; Wei Tang; Shiming Bao; Zhiqiang Yan; Dangsheng Li; Jinsong Li
Journal:  Cell Stem Cell       Date:  2013-12-05       Impact factor: 24.633

8.  Estimation of proportion of new mutants among cases of Duchenne muscular dystrophy.

Authors:  A M Davie; A E Emery
Journal:  J Med Genet       Date:  1978-10       Impact factor: 6.318

9.  Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

Authors:  Hao Yin; Wen Xue; Sidi Chen; Roman L Bogorad; Eric Benedetti; Markus Grompe; Victor Koteliansky; Phillip A Sharp; Tyler Jacks; Daniel G Anderson
Journal:  Nat Biotechnol       Date:  2014-03-30       Impact factor: 54.908

  9 in total

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