Neta Cohen1, Tali Capua, Efraim Bilavsky, Hila Dias-Polak, Dror Levin, Galia Grisaru-Soen.
Abstract
UNLABELLED: Ecthyma gangrenosum (EG) is an uncommon skin lesion that usually develops in patients with known immune deficiency or who are on immunosuppressive treatment. We report on five previously healthy children presenting with EG. Three of them developed severe neutropaenia. Immunologic work-up revealed chronic neutropaenia in two.
CONCLUSION: Recognition of EG is essential for providing early appropriate empiric antibiotic treatment. An immunologic work-up should be done, although a concomitant viral infection can be the predisposing factor. ©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
UNLABELLED: Ecthyma gangrenosum (EG) is an uncommon skin lesion that usually develops in patients with known immune deficiency or who are on immunosuppressive treatment. We report on five previously healthy children presenting with EG. Three of them developed severe neutropaenia. Immunologic work-up revealed chronic neutropaenia in two.
CONCLUSION: Recognition of EG is essential for providing early appropriate empiric antibiotic treatment. An immunologic work-up should be done, although a concomitant viral infection can be the predisposing factor. ©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
Entities:
Keywords:
Ecthyma gangrenosum; Healthy children; Pseudomonas aeruginosa; Skin lesions
Mesh：
Year: 2015
PMID： 25469722 DOI： 10.1111/apa.12889
Source DB: PubMed Journal: Acta Paediatr ISSN： 0803-5253 Impact factor: 2.299