Literature DB >> 25469399

Are biofortified staple food crops improving vitamin A and iron status in women and children? New evidence from efficacy trials.

Fabiana F De Moura, Amanda C Palmer, Julia L Finkelstein, Jere D Haas, Laura E Murray-Kolb, Michael J Wenger, Ekin Birol, Erick Boy, Juan Pablo Peña-Rosas.   

Abstract

Biofortification is the breeding of crops to increase their nutritional value, including increased contents of micronutrients or their precursors. Biofortification aims to increase nutrient levels in crops during plant growth rather than during processing of the crops into foods. Emerging research from 8 human trials conducted in the past decade with staple food crops that have been biofortified by traditional plant breeding methods were presented in this symposium. Specifically, data from 6 efficacy and 2 effectiveness trials were discussed to assess the effects of regular consumption of these enhanced staple crops on improving population vitamin A and iron status and reducing the burden of micronutrient deficiencies in targeted populations living in South Asia, Sub-Saharan Africa, and Latin America. Biofortified food crops appear to have a positive impact on nutritional and functional health outcomes, as the results from the trials suggest. Additional implementation research will be needed to ensure maximization of the beneficial impact of this intervention and a smooth scaling up to make biofortification a sustainable intervention in public health. The challenge for the global health community remains how to take this efficacious intervention and implement at large scale in the real world.

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Year:  2014        PMID: 25469399      PMCID: PMC4188236          DOI: 10.3945/an.114.006627

Source DB:  PubMed          Journal:  Adv Nutr        ISSN: 2161-8313            Impact factor:   8.701


  5 in total

1.  A large-scale intervention to introduce orange sweet potato in rural Mozambique increases vitamin A intakes among children and women.

Authors:  Christine Hotz; Cornelia Loechl; Alan de Brauw; Patrick Eozenou; Daniel Gilligan; Mourad Moursi; Bernardino Munhaua; Paul van Jaarsveld; Alicia Carriquiry; J V Meenakshi
Journal:  Br J Nutr       Date:  2011-10-10       Impact factor: 3.718

Review 2.  Iron deficiency and reduced work capacity: a critical review of the research to determine a causal relationship.

Authors:  J D Haas; T Brownlie
Journal:  J Nutr       Date:  2001-02       Impact factor: 4.798

3.  Introduction of β-carotene-rich orange sweet potato in rural Uganda resulted in increased vitamin A intakes among children and women and improved vitamin A status among children.

Authors:  Christine Hotz; Cornelia Loechl; Abdelrahman Lubowa; James K Tumwine; Grace Ndeezi; Agnes Nandutu Masawi; Rhona Baingana; Alicia Carriquiry; Alan de Brauw; Jonnalagadda V Meenakshi; Daniel O Gilligan
Journal:  J Nutr       Date:  2012-08-08       Impact factor: 4.798

4.  Nutrition-sensitive interventions and programmes: how can they help to accelerate progress in improving maternal and child nutrition?

Authors:  Marie T Ruel; Harold Alderman
Journal:  Lancet       Date:  2013-06-06       Impact factor: 79.321

5.  Iron-biofortified rice improves the iron stores of nonanemic Filipino women.

Authors:  Jere D Haas; John L Beard; Laura E Murray-Kolb; Angelita M del Mundo; Angelina Felix; Glenn B Gregorio
Journal:  J Nutr       Date:  2005-12       Impact factor: 4.798

  5 in total
  15 in total

1.  Combining food-based dietary recommendations using Optifood with zinc-fortified water potentially improves nutrient adequacy among 4- to 6-year-old children in Kisumu West district, Kenya.

Authors:  Prosper Kujinga; Karin J Borgonjen-van den Berg; Cecilia Superchi; Hermine J Ten Hove; Elizabeth Opiyo Onyango; Pauline Andang'o; Valeria Galetti; Michael B Zimmerman; Diego Moretti; Inge D Brouwer
Journal:  Matern Child Nutr       Date:  2017-09-19       Impact factor: 3.092

Review 2.  Review: The potential of the common bean (Phaseolus vulgaris) as a vehicle for iron biofortification.

Authors:  Nicolai Petry; Erick Boy; James P Wirth; Richard F Hurrell
Journal:  Nutrients       Date:  2015-02-11       Impact factor: 5.717

Review 3.  Nutritionally enhanced food crops; progress and perspectives.

Authors:  Kathleen L Hefferon
Journal:  Int J Mol Sci       Date:  2015-02-11       Impact factor: 5.923

Review 4.  The Combined Application of the Caco-2 Cell Bioassay Coupled with In Vivo (Gallus gallus) Feeding Trial Represents an Effective Approach to Predicting Fe Bioavailability in Humans.

Authors:  Elad Tako; Haim Bar; Raymond P Glahn
Journal:  Nutrients       Date:  2016-11-18       Impact factor: 5.717

Review 5.  Finger on the Pulse: Pumping Iron into Chickpea.

Authors:  Grace Z H Tan; Sudipta S Das Bhowmik; Thi M L Hoang; Mohammad R Karbaschi; Alexander A T Johnson; Brett Williams; Sagadevan G Mundree
Journal:  Front Plant Sci       Date:  2017-10-13       Impact factor: 5.753

Review 6.  Iron-biofortified staple food crops for improving iron status: a review of the current evidence.

Authors:  Julia L Finkelstein; Jere D Haas; Saurabh Mehta
Journal:  Curr Opin Biotechnol       Date:  2017-01-25       Impact factor: 9.740

Review 7.  Improving nutrition through biofortification: A review of evidence from HarvestPlus, 2003 through 2016.

Authors:  Howarth E Bouis; Amy Saltzman
Journal:  Glob Food Sec       Date:  2017-03

8.  Studies of Cream Seeded Carioca Beans (Phaseolus vulgaris L.) from a Rwandan Efficacy Trial: In Vitro and In Vivo Screening Tools Reflect Human Studies and Predict Beneficial Results from Iron Biofortified Beans.

Authors:  Elad Tako; Spenser Reed; Amrutha Anandaraman; Steve E Beebe; Jonathan J Hart; Raymond P Glahn
Journal:  PLoS One       Date:  2015-09-18       Impact factor: 3.240

9.  A novel device for assessing dark adaptation in field settings.

Authors:  Alain B Labrique; Amanda C Palmer; Katherine Healy; Sucheta Mehra; Theodor C Sauer; Keith P West; Alfred Sommer
Journal:  BMC Ophthalmol       Date:  2015-07-09       Impact factor: 2.209

10.  Evaluation of Palm Oil as a Suitable Vegetable Oil for Vitamin A Fortification Programs.

Authors:  Marc Pignitter; Natalie Hernler; Mathias Zaunschirm; Julia Kienesberger; Mark Manuel Somoza; Klaus Kraemer; Veronika Somoza
Journal:  Nutrients       Date:  2016-06-21       Impact factor: 5.717

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