Literature DB >> 25468919

Novel approaches to pulmonary fibrosis.

Gisli Jenkins1, Amanda Goodwin2.   

Abstract

Idiopathic pulmonary fibrosis (IPF) is a devastating condition with a poor prognosis and few treatment options. However, recent research into this condition has led to considerable insights into the pathophysiology of the disease, resulting in the identification of potential biomarkers to aid diagnosis and stratification of patients and the development of novel therapies. In this review we will discuss the recent developments in this field and review how this knowledge has been translated into clinical trials and a paradigm shift in our approach to patients with IPF.
© 2014 Royal College of Physicians.

Entities:  

Keywords:  Idiopathic pulmonary fibrosis; biomarkers; nintedanib; pirfenidone

Mesh:

Substances:

Year:  2014        PMID: 25468919     DOI: 10.7861/clinmedicine.14-6-s45

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  6 in total

1.  The protection of glycyrrhetinic acid (GA) towards acetaminophen (APAP)-induced toxicity partially through fatty acids metabolic pathway.

Authors:  Hua Yang; Tingshu Jiang; Ping Li; Qishan Mao
Journal:  Afr Health Sci       Date:  2015-09       Impact factor: 0.927

2.  Protective Effect of Infliximab, a Tumor Necrosis Factor-Alfa Inhibitor, on Bleomycin-Induced Lung Fibrosis in Rats.

Authors:  Nejat Altintas; Mustafa Erboga; Cevat Aktas; Bulent Bilir; Murat Aydin; Aysun Sengul; Zehra Ates; Birol Topcu; Ahmet Gurel
Journal:  Inflammation       Date:  2016-02       Impact factor: 4.092

3.  Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients.

Authors:  Hagai Yanai; Albert Shteinberg; Ziv Porat; Arie Budovsky; Alex Braiman; Rolf Ziesche; Rolf Zeische; Vadim E Fraifeld
Journal:  Aging (Albany NY)       Date:  2015-09       Impact factor: 5.682

4.  Increased Cellular NAD+ Level through NQO1 Enzymatic Action Has Protective Effects on Bleomycin-Induced Lung Fibrosis in Mice.

Authors:  Gi-Su Oh; Su-Bin Lee; Anjani Karna; Hyung-Jin Kim; AiHua Shen; Arpana Pandit; SeungHoon Lee; Sei-Hoon Yang; Hong-Seob So
Journal:  Tuberc Respir Dis (Seoul)       Date:  2016-10-05

5.  Membrane particles from mesenchymal stromal cells reduce the expression of fibrotic markers on pulmonary cells.

Authors:  Ana Merino; Martin J Hoogduijn; Maria Molina-Molina; Elena G Arias-Salgado; Sander S Korevaar; Carla C Baan; Ana Montes-Worboys
Journal:  PLoS One       Date:  2021-03-17       Impact factor: 3.240

6.  MMP-7 is a predictive biomarker of disease progression in patients with idiopathic pulmonary fibrosis.

Authors:  Yasmina Bauer; Eric S White; Simon de Bernard; Peter Cornelisse; Isabelle Leconte; Adele Morganti; Sebastien Roux; Oliver Nayler
Journal:  ERJ Open Res       Date:  2017-03-22
  6 in total

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