Literature DB >> 25468052

Prediction of neonatal respiratory distress syndrome in term pregnancies by assessment of fetal lung volume and pulmonary artery resistance index.

Mohamed Laban1, Ghada M Mansour2, Mohammed S E Elsafty2, Alaa S Hassanin2, Sahar S EzzElarab3.   

Abstract

OBJECTIVE: To develop reference cutoff values for mean fetal lung volume (FLV) and pulmonary artery resistance index (PA-RI) for prediction of neonatal respiratory distress syndrome (RDS) in low-risk term pregnancies.
METHODS: As part of a cross-sectional study, women aged 20-35 years were enrolled and admitted to a tertiary hospital in Cairo, Egypt, for elective repeat cesarean at 37-40 weeks of pregnancy between January 1, 2012, and July 31, 2013. FLV was calculated by virtual organ computer-aided analysis, and PA-RI was measured by Doppler ultrasonography before delivery.
RESULTS: A total of 80 women were enrolled. Neonatal RDS developed in 11 (13.8%) of the 80 newborns. Compared with neonates with RDS, healthy neonates had significantly higher FLVs (P<0.001) and lower PA-RIs (P<0.001). Neonatal RDS is less likely with FLV of at least 32 cm(3) or PA-RI less than or equal to 0.74. Combining these two measures improved the accuracy of prediction.
CONCLUSION: The use of either FLV or PA-RI predicted neonatal RDS. The predictive value increased when these two measures were combined.
Copyright © 2014 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Fetal lung volume; Fetal pulmonary artery Doppler; Neonatal respiratory distress syndrome; Pulmonary artery resistance index; Three-dimensional ultrasonography; Virtual organ computer-aided analysis

Mesh:

Year:  2014        PMID: 25468052     DOI: 10.1016/j.ijgo.2014.09.018

Source DB:  PubMed          Journal:  Int J Gynaecol Obstet        ISSN: 0020-7292            Impact factor:   3.561


  3 in total

1.  Prenatal prediction of respiratory distress syndrome by multimodality approach using 3D lung ultrasound, lung-to-liver intensity ratio tissue histogram and pulmonary artery Doppler assessment of fetal lung maturity.

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Journal:  J Clin Lab Anal       Date:  2019-12-05       Impact factor: 2.352

  3 in total

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