Literature DB >> 25467757

Hippo pathway in mammary gland development and breast cancer.

Peiguo Shi1, Jing Feng2, Ceshi Chen3.   

Abstract

Accumulated evidence suggests that the Hippo signaling pathway plays crucial roles in mammary gland development and breast cancer. Key components of the Hippo pathway regulate breast epithelial cell proliferation, migration, invasion, and stemness. Additionally, the Hippo pathway regulates breast tumor growth, metastasis, and drug resistance. It is expected that the Hippo pathway will provide novel therapeutic targets for breast cancer. This review will discuss and summarize the roles of several core components of the Hippo pathway in mammary gland development and breast cancer.
© The Author 2014. Published by ABBS Editorial Office in association with Oxford University Press on behalf of the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences.

Entities:  

Keywords:  Hippo pathway; TAZ; YAP; breast cancer; mammary gland development

Mesh：

Substances：

Year:  2014        PMID： 25467757     DOI： 10.1093/abbs/gmu114

Source DB:  PubMed          Journal:  Acta Biochim Biophys Sin (Shanghai)        ISSN： 1672-9145            Impact factor:   3.848


  27 in total

1.  In Vitro Validation of the Hippo Pathway as a Pharmacological Target for Canine Mammary Gland Tumors.

Authors:  Samantha Guillemette; Charlène Rico; Philippe Godin; Derek Boerboom; Marilène Paquet
Journal:  J Mammary Gland Biol Neoplasia       Date:  2017-08-18       Impact factor: 2.673

2.  Upregulation of Yes-associated protein and transcriptional co-activator with PDZ-binding motif influences the behavior of LOVO human colon adenocarcinoma cells.

Authors:  Yu Li; Lan Li; Min Zhu; Limin Ye; Qian Yang
Journal:  Exp Ther Med       Date:  2017-08-18       Impact factor: 2.447

Review 3.  Molecular targets and therapeutics in chemoresistance of triple-negative breast cancer.

Authors:  Arijit Nath; Soham Mitra; Tanuma Mistry; Ranita Pal; Vilas D Nasare
Journal:  Med Oncol       Date:  2021-11-23       Impact factor: 3.064

4.  Up-regulation of miR-506 inhibits cell growth and disrupt the cell cycle by targeting YAP in breast cancer cells.

Authors:  Kaiyao Hua; Weiguo Yang; Hongming Song; Jialu Song; Chuankui Wei; Dengfeng Li; Lin Fang
Journal:  Int J Clin Exp Med       Date:  2015-08-15

Review 5.  The Role of the Hippo Pathway in Breast Cancer Carcinogenesis, Prognosis, and Treatment: A Systematic Review.

Authors:  Anastasios Kyriazoglou; Michalis Liontos; Roubini Zakopoulou; Maria Kaparelou; Anna Tsiara; Alkistis Maria Papatheodoridi; Rebecca Georgakopoulou; Flora Zagouri
Journal:  Breast Care (Basel)       Date:  2020-05-12       Impact factor: 2.860

6.  BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells.

Authors:  Wesley D Frey; Anisha Chaudhry; Priscila F Slepicka; Adam M Ouellette; Steven E Kirberger; William C K Pomerantz; Gregory J Hannon; Camila O Dos Santos
Journal:  Stem Cell Reports       Date:  2017-06-01       Impact factor: 7.765

7.  TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway.

Authors:  X Su; M Napoli; H A Abbas; A Venkatanarayan; N H B Bui; C Coarfa; Y J Gi; F Kittrell; P H Gunaratne; D Medina; J M Rosen; F Behbod; E R Flores
Journal:  Oncogene       Date:  2016-11-21       Impact factor: 9.867

8.  Bioinformatic identification of chemoresistance-associated microRNAs in breast cancer based on microarray data.

Authors:  Ya-Wen Wang; Weiguo Zhang; Rong Ma
Journal:  Oncol Rep       Date:  2018-01-10       Impact factor: 3.906

9.  The Hippo Signaling Transducer TAZ Regulates Mammary Gland Morphogenesis and Carcinogen-induced Mammary Tumorigenesis.

Authors:  Kayla E Denson; Ashley L Mussell; He Shen; Alexander Truskinovsky; Nuo Yang; Natesh Parashurama; Yanmin Chen; Costa Frangou; Fajun Yang; Jianmin Zhang
Journal:  Sci Rep       Date:  2018-04-24       Impact factor: 4.379

10.  Fibroblasts in Head and Neck Squamous Cell Carcinoma Associated With Perineural Invasion Have High-Level Nuclear Yes-Associated Protein (YAP) Expression.

Authors:  Yanghua Wang; Adam Gersten; Susana Moleirinho; Frank J Gunn-Moore; Paul A Reynolds; Michael B Prystowsky
Journal:  Acad Pathol       Date:  2015-11-26
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