Literature DB >> 25467388

Outcome of different oncoplastic surgical (OPs) techniques for centrally located breast cancer (CLBC).

A Moustafa1, I Fakhr2.   

Abstract

BACKGROUND: Oncoplastic breast surgery is a standard treatment of early breast cancer, offering a balance between good cosmetic outcome and limited risk of locoregional recurrence, by enabling proper resection margins.
AIM OF STUDY: To present multiple techniques of partial breast reconstruction following the resection of centrally located breast cancer (CLBC) resection. PATIENTS AND METHODS: From January 2011 to August 2014, 21 patients underwent central quadrantectomy for carcinoma of the central region of the breast. Excisions included the nipple/areola complex, in most of the cases, down to the pectoralis fascia with a wide safety margin, and proper axillary management. Oncoplastic approaches included latissimus dorsi flap, inferior pedicle flap, Melon slice, Grisotti and round block techniques.
RESULTS: Mean age of patients was 49.5±10.61 years. Tumor size ranged from 1.5 to 4.5 cm. Postoperative pathology revealed a tumor mean safety margin of 2.5±0.83 cm, with positive axillary lymph nodes in 15 (75.0%) patients. Nineteen (95.0%) patients received postoperative breast radiotherapy, while 9/20 (45.0%) and 3/20 (15.0%) received adjuvant chemotherapy or hormonal therapy, respectively, and only 8/20 (40.0%) patients received both therapies. During a median follow-up period of 14.89 months, neither local nor distant metastasis, were detected. The postoperative cosmetic result evaluated by the patients was excellent in 6/20 patients (30.0%), good in 11/20 patients (55.0%), fair in 3/20 (15.0%) with neither poor nor bad results, with an overall mean of 4.0±0.5 equivalent to 80% satisfaction.
CONCLUSION: Multiple oncoplastic breast surgery techniques can be used for the resection of CLBC with satisfying cosmetic outcomes.
Copyright © 2014. Production and hosting by Elsevier B.V.

Entities:  

Keywords:  Central breast cancer; Grisotti procedure; Inferior pedicle flap; Latissimus dorsi (LD) flap; Melon slice; Oncoplastic breast surgery (OBS); Round block technique (Donut Mastopexy Resection)

Mesh:

Year:  2014        PMID: 25467388     DOI: 10.1016/j.jnci.2014.10.003

Source DB:  PubMed          Journal:  J Egypt Natl Canc Inst        ISSN: 1110-0362


  6 in total

1.  Therapeutic effects of cytoprotective agent on breast reconstruction after breast cancer surgery.

Authors:  Xinjia He; Lihua Wang; Wei Li; Zhuang Yu; Xingang Wang
Journal:  Int J Clin Exp Med       Date:  2015-11-15

Review 2.  Oncoplastic central quadrantectomies.

Authors:  Vittorio Pasta; Valerio D'Orazi; Raffaele Merola; Federico Frusone; Maria Ida Amabile; Alessandro De Luca; Rosanna Buè; Marco Monti
Journal:  Gland Surg       Date:  2016-08

3.  Oncoplastic surgery for the conservative treatment of breast cancer in Perú's National Cancer Institute.

Authors:  Gonzalo Javier Ziegler Rodriguez; Marcelo Diaz Chavez; Gabriela Guadalupe Calderon Valencia; Jose Manuel Cotrina Concha; Milko Raphael Garces Castre; Raul Mantilla
Journal:  Ecancermedicalscience       Date:  2018-03-01

4.  Immediate Breast Reconstruction of a Nipple Areolar Lumpectomy Defect With the L-Flap Skin Paddle Breast Reduction Design and Contralateral Reduction Mammoplasty Symmetry Procedure: Optimizing the Oncoplastic Surgery Multispecialty Approach.

Authors:  Mitchell Buller; Adee Heiman; Jared Davis; Thomas J Lee; Nicolás Ajkay; Bradon J Wilhelmi
Journal:  Eplasty       Date:  2017-03-31

5.  Sec23a mediates miR-200c augmented oligometastatic to polymetastatic progression.

Authors:  Zhiwei Sun; Shixia Zhou; Junling Tang; Ting Ye; Jingyuan Li; Doudou Liu; Jian Zhou; Jianyu Wang; H Rosie Xing
Journal:  EBioMedicine       Date:  2018-10-06       Impact factor: 8.143

6.  Extreme oncoplasty for centrally located breast cancer in small non-ptotic breasts: extending the indications of chest wall perforator flaps with areolar reconstruction.

Authors:  Shashank Nigam; Andrew Eichholz; Madhu Bhattacharyya; Vaishali Parulekar; Pankaj Gupta Roy
Journal:  Ecancermedicalscience       Date:  2021-11-01
  6 in total

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