INTRODUCTION: Mixed-species biofilms are involved in a wide variety of infections. We studied the synergistic interactions during dual-species biofilm formation among isolates of Pseudomonas aeruginosa, Acinetobacter baumannii, and Stenotrophomonas maltophilia. METHODS: Isolates were cultured as single-species and all possible combinations of dual-species biofilms. RESULTS: The 61 A. baumannii biofilms increased by 26-fold when cultured with S. maltophilia isolates; 62 A. baumannii biofilms increased by 20-fold when cultured with S. maltophilia isolates; and 31 P. aeruginosa biofilms increased by 102-fold when cultured with S. maltophilia 106. CONCLUSIONS: Synergy was observed between two isolates, including those that inherently lacked biofilm formation ability.
INTRODUCTION: Mixed-species biofilms are involved in a wide variety of infections. We studied the synergistic interactions during dual-species biofilm formation among isolates of Pseudomonas aeruginosa, Acinetobacter baumannii, and Stenotrophomonas maltophilia. METHODS: Isolates were cultured as single-species and all possible combinations of dual-species biofilms. RESULTS: The 61 A. baumannii biofilms increased by 26-fold when cultured with S. maltophilia isolates; 62 A. baumannii biofilms increased by 20-fold when cultured with S. maltophilia isolates; and 31 P. aeruginosa biofilms increased by 102-fold when cultured with S. maltophilia 106. CONCLUSIONS: Synergy was observed between two isolates, including those that inherently lacked biofilm formation ability.
Authors: Xiaoxi B Lin; Tuo Wang; Paul Stothard; Jukka Corander; Jun Wang; John F Baines; Sarah C L Knowles; Laima Baltrūnaitė; Guergana Tasseva; Robert Schmaltz; Stephanie Tollenaar; Liz A Cody; Theodore Grenier; Wei Wu; Amanda E Ramer-Tait; Jens Walter Journal: ISME J Date: 2018-07-16 Impact factor: 10.302