Literature DB >> 25467095

Evolution in the profile of thyroid cancer cases treated in an oncology reference service: what changed in the last 20 years.

Renan Bezerra Lira1, Genival Barbosa de Carvalho1, João Gonçalves Filho1, Luiz Paulo Kowalski1.   

Abstract

OBJECTIVE: To evaluate the characteristics of thyroid carcinoma cases treated at a reference hospital for cancer between 2008 and 2010.
METHODS: we studied 807 cases and analyzed the following clinicopathologic variables: symptoms, risk factors, diagnostic tests, staging, histological type, treatment performed and complications.
RESULTS: Females were more affected, with 660 cases (82%). The average age at diagnosis was 44.5 years. Prior exposure to ionizing radiation was reported by 22 (3%) patients, a family history of thyroid cancer by 89 (11%), and 289 (36%) individuals reported other types of cancer in the family. The fine needle aspiration biopsy was the main parameter for surgical indication and was suggestive of carcinoma in 463 patients (57%). Papillary carcinoma was the most common histological type, with 780 cases (96.6%). There were 728 (90%) total thyroidectomies, 43 (5.3%) reoperations or partial thyroidectomies followed by totalization, 23 (2.8%) extended thyroidectomies and only 13 (1.6%) partial thyroidectomies (lobectomy with isthmectomy). Neck dissection associated with thyroidectomy was done in 158 patients (19.5%). We observed a predominance of tumors classified as T1 in 602 (74.6%) patients. Transient hypocalcemia was the most frequent complication.
CONCLUSION: The results show that the worldwide increase in the incidence of thyroid cancer has changed the profile of patients seen at a referral service. In addition, there were changes in the type of surgical treatment used, with increased use of total thyroidectomy in relation to partial and subtotal ones, and decreased use of elective neck dissections.

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Year:  2014        PMID: 25467095     DOI: 10.1590/0100-69912014005004

Source DB:  PubMed          Journal:  Rev Col Bras Cir        ISSN: 0100-6991


  2 in total

1.  Variations and results of retroauricular robotic thyroid surgery associated or not with neck dissection.

Authors:  Renan Bezerra Lira; Thiago Celestino Chulam; Luiz Paulo Kowalski
Journal:  Gland Surg       Date:  2018-08

2.  Characterization of BRAF mutation in patients older than 45 years with well-differentiated thyroid carcinoma.

Authors:  Luis Rene Quiroa Barreno; Julia Bette Homem de Mello; Mateus Camargo Barros-Filho; Ana Lucia Francisco; Thiago Celestino Chulam; Clovis Antonio Lopes Pinto; Joao Gonçalves-Filho; Luiz Paulo Kowalski
Journal:  Braz J Otorhinolaryngol       Date:  2020-09-12
  2 in total

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