Giordano Tasca1, Riccardo Vismara2, Gianfranco Beniamino Fiore2, Claudia Romagnoni3, Alberto Redaelli2, Carlo Antona3, Amando Gamba4. 1. Cardiac Surgery Unit, Cardiovascular Department, A. Manzoni Hospital, Lecco, Italy; Department of Electronic Information and Bioengineering, Politecnico di Milano, Milan, Italy. Electronic address: giordano.tasca67@gmail.com. 2. Department of Electronic Information and Bioengineering, Politecnico di Milano, Milan, Italy; ForCardio.lab, Fondazione per la Ricerca in Cardiochirurgia ONLUS, Milan, Italy. 3. ForCardio.lab, Fondazione per la Ricerca in Cardiochirurgia ONLUS, Milan, Italy; Cardiovascular Surgery Department, L. Sacco Hospital, Università degli Studi di Milano, Milan, Italy. 4. Cardiac Surgery Unit, Cardiovascular Department, A. Manzoni Hospital, Lecco, Italy.
Abstract
BACKGROUND: The in vivo hemodynamic performance of a bioprosthesis implanted in an aortic position is affected by the characteristics of the prosthesis and the sizing strategy adopted. Recently, it has been hypothesized that the type of suture used to implant the prosthesis might influence hemodynamics. METHODS: Bioprostheses with labeled sizes of 19 mm and 21 mm were implanted in 2 groups of 5 porcine aortic roots, with native annuli of 19 mm and 21 mm, by means of 2 different suture techniques: simple interrupted and noneverting mattress with pledgets. The aortic roots were tested in an in vitro mock loop. The stroke volume imposed by the mock loop was set at 40 mL, and was increased by steps of 15 mL until a stroke volume of 100 mL was attained. Main fluid-dynamic parameters were analyzed. RESULTS: At each level of stroke volume, ie, 40 mL, 55 mL, 70 mL, 85 mL, and 100 mL, the mean and peak pressure drops were significantly greater with the noneverting mattress suture with pledgets than with the simple interrupted suture. The effective orifice area behaved accordingly, being significantly smaller in the former case. CONCLUSIONS: Our data show that the type of suture technique can influence bioprosthesis performance and that it is reasonable to assume that this is especially true in small annuli (≤ 21 mm). Thus, to optimize prosthesis performance and reduce the incidence of patient-prosthesis mismatch, the role of the suture technique should not be disregarded.
BACKGROUND: The in vivo hemodynamic performance of a bioprosthesis implanted in an aortic position is affected by the characteristics of the prosthesis and the sizing strategy adopted. Recently, it has been hypothesized that the type of suture used to implant the prosthesis might influence hemodynamics. METHODS: Bioprostheses with labeled sizes of 19 mm and 21 mm were implanted in 2 groups of 5 porcine aortic roots, with native annuli of 19 mm and 21 mm, by means of 2 different suture techniques: simple interrupted and noneverting mattress with pledgets. The aortic roots were tested in an in vitro mock loop. The stroke volume imposed by the mock loop was set at 40 mL, and was increased by steps of 15 mL until a stroke volume of 100 mL was attained. Main fluid-dynamic parameters were analyzed. RESULTS: At each level of stroke volume, ie, 40 mL, 55 mL, 70 mL, 85 mL, and 100 mL, the mean and peak pressure drops were significantly greater with the noneverting mattress suture with pledgets than with the simple interrupted suture. The effective orifice area behaved accordingly, being significantly smaller in the former case. CONCLUSIONS: Our data show that the type of suture technique can influence bioprosthesis performance and that it is reasonable to assume that this is especially true in small annuli (≤ 21 mm). Thus, to optimize prosthesis performance and reduce the incidence of patient-prosthesis mismatch, the role of the suture technique should not be disregarded.
Authors: Martin Andreas; Stephanie Wallner; Andreas Habertheuer; Claus Rath; Martin Schauperl; Thomas Binder; Dietrich Beitzke; Raphael Rosenhek; Christian Loewe; Dominik Wiedemann; Alfred Kocher; Guenther Laufer Journal: Interact Cardiovasc Thorac Surg Date: 2016-03-13
Authors: Claudio Capelli; Chiara Corsini; Dario Biscarini; Francesco Ruffini; Francesco Migliavacca; Alfred Kocher; Guenther Laufer; Andrew M Taylor; Silvia Schievano; Martin Andreas; Gaetano Burriesci; Claus Rath Journal: Cardiovasc Eng Technol Date: 2016-11-21 Impact factor: 2.495