Literature DB >> 25466360

A unique approach to high-dose-rate vaginal mold brachytherapy of gynecologic malignancies.

Sanna Nilsson1, Zoë Moutrie2, Robyn Cheuk2, Philip Chan2, Craig Lancaster2, Tim Markwell3, Jodi Dawes2, Phil Back2.   

Abstract

PURPOSE: Patients with cervical and vaginal cancer sometimes have a less straightforward approach for choice of brachytherapy treatment owing to the tumor's location and clinical presentation. The staff at Royal Brisbane & Women's Hospital in Queensland, Australia, is trying to solve this problem by the use of an old technique in a new approach called vaginal molds. With a patient-specific vaginal mold, the appearance of the applicator and the dose distribution can be customized to provide an optimal treatment for each patient. METHODS AND MATERIALS: The technique used at the Royal Brisbane & Women's Hospital uses a flexible two-part putty, moulded to the shape of the vagina, in which standard catheters (flexible implant tubes) are incorporated, in a pattern designed to permit a dose distribution more conformal to the target volume.
RESULTS: The presented technique is efficient and improves the accuracy of a homogeneous target cover and sparing of organs at risk for vaginal mold brachytherapy treatments at our institution.
CONCLUSION: This technique offers a customizable option when traditional cylindrical- or dome-type applicators cannot be used, or provide inadequate dose coverage. Molds to match the patient anatomy can be created quickly, while allowing flexibility in positioning of catheters to achieve the desired dose distribution.
Copyright © 2015 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Applicator; Brachytherapy; Cervical cancer; Fusion; Vaginal cancer; Vaginal mold

Mesh:

Year:  2014        PMID: 25466360     DOI: 10.1016/j.brachy.2014.10.004

Source DB:  PubMed          Journal:  Brachytherapy        ISSN: 1538-4721            Impact factor:   2.362


  5 in total

Review 1.  Vaginal cuff brachytherapy in endometrial cancer - a technically easy treatment?

Authors:  Sebastià Sabater; Ignacio Andres; Veronica Lopez-Honrubia; Roberto Berenguer; Marimar Sevillano; Esther Jimenez-Jimenez; Angeles Rovirosa; Meritxell Arenas
Journal:  Cancer Manag Res       Date:  2017-08-09       Impact factor: 3.989

2.  Development and preclinical testing of a novel biodegradable hydrogel vaginal packing technology for gynecologic high-dose-rate brachytherapy.

Authors:  Matthew Sean Peach; Joanna Moore; Wallis Giles; Justin Trainor; Tim Long; Nicholas Moon; Joseph E Hylton; Timothy N Showalter; Bruce Libby
Journal:  J Contemp Brachytherapy       Date:  2018-08-31

3.  Manufacturing and evaluation of multi-channel cylinder applicator with 3D printing technology.

Authors:  Reza Mohammadi; Zahra Siavashpour; Seyed Rashid Hosseini Aghdam; Samar Fazli; Tibor Major; Ali Asghar Rohani
Journal:  J Contemp Brachytherapy       Date:  2021-02-18

4.  Comparing multichannel cylinder and 3D-printed applicators for vaginal cuff brachytherapy with preliminary exploration of post-hysterectomy vaginal morphology.

Authors:  Junfang Yan; Xue Qin; Fuquan Zhang; Xiaorong Hou; Lang Yu; Jie Qiu
Journal:  J Contemp Brachytherapy       Date:  2021-12-30

5.  A single-institution review of image-guided brachytherapy for vaginal malignancies using customized molded applicators and interstitial needles.

Authors:  Emily Flower; Salman Zanjani; Gemma Busuttil; Emma Sullivan; Wayne Smith; Kathy Tran; David Thwaites; Jennifer Chard; Viet Do
Journal:  J Contemp Brachytherapy       Date:  2021-12-30
  5 in total

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