| Literature DB >> 25465752 |
Zhiyong Li1, Wenying Mi2, Huiliang Wang2, Yunlan Su3, Changcheng He4.
Abstract
Nano-hydroxyapatite/polyacrylamide composite hydrogels were successfully fabricated by physically mixing nano-hydroxyapatite (nHAp) particles into a peroxidized micelles initiated and cross-linked (pMIC) polyacrylamide (PAAm) hydrogel. The nanocomposite hydrogels exhibited excellent mechanical properties. The fracture tensile stresses of the gels were in the range of 0.21-0.86 MPa and the fracture tensile strains were up to 30 mm/mm, and the compressive strengths were up to 35.8 MPa. Meanwhile the introduction of nHAp endowed the composite hydrogels with good cell adhesion properties. This nHAp/PAAm nanocomposite hydrogel is expected to find potential applications in tissue engineering.Entities:
Keywords: Composite hydrogel; Hydroxyapatite; Mechanical property; Polyacrylamide; Tissue engineering
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Year: 2014 PMID: 25465752 DOI: 10.1016/j.colsurfb.2014.10.050
Source DB: PubMed Journal: Colloids Surf B Biointerfaces ISSN: 0927-7765 Impact factor: 5.268