| Literature DB >> 25464112 |
Liyang Jiang1, Xin Zhao2, Xue Meng1, Jinming Yu3.
Abstract
Esophageal cancer (EC) is an extremely aggressive and lethal malignancy with an increasing incidence worldwide. Currently, the combination of radiotherapy and concurrent chemotherapy is performed for nonsurgical EC. However, there is no clear consensus on the accurate definition of the clinical target volume. Still, elective nodal irradiation (ENI) is the conventional remedy adopted for EC patients, while severe radiotherapy-related toxicities would occur in at least half of patients. Involved field irradiation (IFI) is a selective way to decrease the irradiation volume and thereby to decline toxicities. This review centers on the modality of IFI and compares the treatment efficacy between IFI and ENI.Entities:
Keywords: Elective nodal irradiation; Esophageal cancer; Involved field irradiation
Mesh：
Year: 2014 PMID： 25464112 DOI： 10.1016/j.canlet.2014.11.045
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679