| Literature DB >> 25462868 |
Tong Liu1, Lusheng Zhu2, Jinhua Wang3, Jun Wang1, Hui Xie1.
Abstract
Although considered as "green" solvents, the toxic effects of ionic liquids (ILs) on organisms have been widely investigated in recent years. However, studies on the toxic effects of ILs on plants all focus on toxicity in nutrient solution. In the present paper, the toxic effects of 1-butyl-3-methylimidazolium chloride ([C4mim]Cl) on Vicia faba seedlings in soil at 0, 500, 1500, and 2500 mg kg(-1) on day 10 were studied. The present results showed that the growth of V. faba seedlings may be seriously inhibited when the IL concentrations were higher than 500 mg kg(-1). The EC50 values for shoot length, root length, and dry weight were 3886, 2483, and 3359 mg kg(-1), respectively. In addition, [C4mim]Cl caused lipid peroxidation and DNA damage at 500 mg kg(-1) and oxidative stress at 1500 mg kg(-1), which indicated that [C4mim]Cl may have genotoxicity and cytotoxicity on V. faba seedlings. Moreover, oxidative damage may be the main toxic mechanism of ILs.Entities:
Keywords: Antioxidase system; DNA damage; EC(50); Lipid peroxidation; ROS
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Year: 2014 PMID： 25462868 DOI： 10.1016/j.jhazmat.2014.11.028
Source DB: PubMed Journal: J Hazard Mater ISSN： 0304-3894 Impact factor: 10.588