Nira A Goldstein1,2, Charlotte Aronin1,2, Beth Kantrowitz1,2, Ronald Hershcopf1,2, Sherry Fishkin1,2, Haesoon Lee3,4, Diana E Weaver3,4, Candice Yip1,2, Christine Liaw1,2, Tehila A Saadia1,2, Jason Abramowitz1,2, Jeremy Weedon5. 1. Division of Pediatric Otolaryngology, State University of New York Downstate Medical Center, Brooklyn, New York. 2. Department of Otolaryngology, Kings County Hospital Center, Brooklyn, New York. 3. Division of Pediatric Pulmonology, State University of New York Downstate Medical Center, Brooklyn, New York. 4. Department of Pediatrics, Kings County Hospital Center, Brooklyn, New York. 5. Scientific Computing Center, State University of New York Downstate Medical Center, Brooklyn, New York.
Abstract
OBJECTIVES: To determine the prevalence of sleep-disordered breathing (SDB) in children with asthma compared to non-asthmatic children and to determine if behavior problems are associated with asthma and SDB. STUDY DESIGN: Cross-Sectional. METHODS: Parents of 263 children with asthma and 266 controls ages 2 to 15 years attending routine pediatric office visits completed the Pediatric Sleep Questionnaire (PSQ) and the Child Behavior Checklist. Asthma severity was classified based on NIH guidelines. RESULTS: The prevalence of snoring was significantly higher in asthmatic children (35.5%) than controls (15.7%) and the prevalence of a positive PSQ was significantly higher in asthmatic children (25.9%) than controls (10.6%) (P < 0.001 for both). The effect of asthma was "dose-dependent" as children with more severe asthma had increased odds ratios for snoring and a positive PSQ. On multivariate analysis, there were significant interactions of gender with asthma and age with gender. A positive modified PSQ along with measures of socioeconomic status and age were the only independent predictors of abnormal Child Behavior Checklist scores and score classifications. CONCLUSIONS: There was a higher prevalence of SDB in asthmatic children compared to non-asthmatic children and the prevalence of SDB increased with increasing asthma severity. In multivariate analysis the role of asthma was much less clear as it predicted a positive PSQ in girls but not boys. SDB, but not asthma, was an independent predictor of behavioral problems.
OBJECTIVES: To determine the prevalence of sleep-disordered breathing (SDB) in children with asthma compared to non-asthmatic children and to determine if behavior problems are associated with asthma and SDB. STUDY DESIGN: Cross-Sectional. METHODS: Parents of 263 children with asthma and 266 controls ages 2 to 15 years attending routine pediatric office visits completed the Pediatric Sleep Questionnaire (PSQ) and the Child Behavior Checklist. Asthma severity was classified based on NIH guidelines. RESULTS: The prevalence of snoring was significantly higher in asthmatic children (35.5%) than controls (15.7%) and the prevalence of a positive PSQ was significantly higher in asthmatic children (25.9%) than controls (10.6%) (P < 0.001 for both). The effect of asthma was "dose-dependent" as children with more severe asthma had increased odds ratios for snoring and a positive PSQ. On multivariate analysis, there were significant interactions of gender with asthma and age with gender. A positive modified PSQ along with measures of socioeconomic status and age were the only independent predictors of abnormal Child Behavior Checklist scores and score classifications. CONCLUSIONS: There was a higher prevalence of SDB in asthmatic children compared to non-asthmatic children and the prevalence of SDB increased with increasing asthma severity. In multivariate analysis the role of asthma was much less clear as it predicted a positive PSQ in girls but not boys. SDB, but not asthma, was an independent predictor of behavioral problems.
Authors: Jennifer A Kannan; Cole Brokamp; David I Bernstein; Grace K LeMasters; Gurjit K Khurana Hershey; Manuel S Villareal; James E Lockey; Patrick H Ryan Journal: Pediatr Allergy Immunol Pulmonol Date: 2017-03-01 Impact factor: 1.349
Authors: Aarti Shakkottai; Samya Z Nasr; Fauziya Hassan; Sanaya Irani; Louise M O'Brien; Ronald D Chervin Journal: Sleep Med Date: 2020-06-05 Impact factor: 3.492