Literature DB >> 25460341

Challenges in conducting a randomized clinical trial of older people with chronic dizziness: before, during and after vestibular rehabilitation.

Natalia A Ricci1, Mayra C Aratani2, Heloísa H Caovilla2, Fernando F Ganança2.   

Abstract

PURPOSE: This study aims to describe the process of conducting a randomized clinical trial of elderly with chronic dizziness subjected to vestibular rehabilitation (VR) and to verify its effectiveness on dizziness intensity.
METHODS: Older adults (≥65 years) with chronic dizziness from vestibular disorders referred to VR were enrolled to the trial. The control group (n=40) was submitted to the Cawthorne & Cooksey protocol and the experimental group (n=42) to the modified Cawthorne & Cooksey protocol which included multiple components. Protocols were performed during individual 50-minute sessions, twice-weekly, for eight weeks. Main measures were: recruitment data (refusal and eligibility), baseline characteristics, dropout rate, session attendance, protocol adherence, adverse effects, exercise adaptation and follow-up events. The Visual Analog Scale (VAS) was used to measure dizziness intensity.
RESULTS: 144 elderly were referred to VR, 26.4% declined to participate and 16.7% were ineligible. There were 51 session non-attendances, with disease being the most frequent reason. Regardless of VR protocol, VAS dizziness intensity diminished along sessions (p<0.001). 88.6% of the participants reported improvement after treatment, and 22.9% mentioned an increase in dizziness on follow-up. Home exercises were no longer being performed by 21.4% of the subjects after 3 months from discharge. The final dropout rate was 14.6%. There were no differences between VR protocols on recruitment, dropout, session's attendance, adherence to protocol and treatment effects.
CONCLUSIONS: Our results revealed many challenges in conducting a rehabilitation trial with an elderly sample. The VR protocols showed to be feasible and suitable to reduce dizziness in older adults.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Dizziness; Elderly; Patient adherence; Patient dropouts; Vestibular rehabilitation

Mesh:

Year:  2014        PMID: 25460341     DOI: 10.1016/j.cct.2014.11.002

Source DB:  PubMed          Journal:  Contemp Clin Trials        ISSN: 1551-7144            Impact factor:   2.226


  3 in total

1.  Vestibular rehabilitation with mobile posturography as a "low-cost" alternative to vestibular rehabilitation with computerized dynamic posturography, in old people with imbalance: a randomized clinical trial.

Authors:  Andrés Soto-Varela; Marcos Rossi-Izquierdo; María Del-Río-Valeiras; Ana Faraldo-García; Isabel Vaamonde-Sánchez-Andrade; Antonio Lirola-Delgado; Sofía Santos-Pérez
Journal:  Aging Clin Exp Res       Date:  2021-03-07       Impact factor: 3.636

2.  Benefits of vestibular rehabilitation on patient-reported outcomes in older adults with vestibular disorders: a randomized clinical trial.

Authors:  Mayra Cristina Aratani; Natalia Aquaroni Ricci; Heloísa Helena Caovilla; Fernando Freitas Ganança
Journal:  Braz J Phys Ther       Date:  2020-01-03       Impact factor: 3.377

3.  Cross-cultural adaptation and validation of the Chinese version of the vestibular activities and participation measure.

Authors:  Peixia Wu; Mei Yang; Yan Hu; Huawei Li
Journal:  J Vestib Res       Date:  2019       Impact factor: 2.354

  3 in total

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