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Literature DB >> 25460291

Sex and sex steroids: impact on the kinetics of fatty acids underlying body shape.

Abstract

Adult humans have a remarkable sexual dimorphism in body shape. Men tend to store relatively more fat in the upper body whereas women store more fat in the lower body. We do not have a complete understanding of the mechanisms underlying these differences, but we know that people who preferentially store abdominal fat are at greater risk of metabolic disease. It is also known that the changes in sex steroid concentrations during puberty and again with advancing age are accompanied by changes in body fat distribution. The objective of this review is to describe what has been learned regarding the mechanisms underlying changes in regional body fat distribution that occur as a result of changes in sex hormones and to delineate effects of sex steroids in modulating body composition.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2014 PMID： 25460291 PMCID： PMC4348027 DOI： 10.1515/hmbci-2014-0029

Source DB: PubMed Journal: Horm Mol Biol Clin Investig ISSN： 1868-1883

78 in total

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4 in total

1. Sex-dependent difference in the relationship between adipose-tissue cholesterol efflux and estradiol concentrations in young healthy humans.

Authors: Fatima Iqbal; William J Durham; Ayyash Melhem; Saleem Raslan; Tony T Tran; Traver J Wright; Rabia Asghar; Ken Fujise; Elena Volpi; Labros Sidossis; Nicola Abate; Melinda Sheffield-Moore; Demidmaa Tuvdendorj
Journal: Int J Dev Neurosci Date: 2017-07-12 Impact factor: 2.457