Elisabeth Haug1, Merete Øie2, Ole A Andreassen3, Unni Bratlien4, Barnaby Nelson5, Monica Aas3, Paul Møller6, Ingrid Melle3. 1. Division of Mental Health, Innlandet Hospital Trust, Ottestad, Norway. Electronic address: elisabeth.haug@sykehuset-innlandet.no. 2. Division of Mental Health, Innlandet Hospital Trust, Ottestad, Norway; Department of Psychology, University of Oslo, Oslo, Norway. 3. NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, Division of Mental Health and Addiction, University of Oslo, and Oslo University Hospital, Oslo, Norway. 4. Division of Mental Health, Innlandet Hospital Trust, Ottestad, Norway. 5. Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Melbourne, Australia. 6. Department of Mental Health Research and Development, Division of Mental Health and Addiction, Vestre Viken Hospital Trust, Drammen, Norway.
Abstract
BACKGROUND: Anomalous self-experiences (ASEs) are viewed as core features of schizophrenia. Childhood trauma (CT) has been postulated as a risk factor for developing schizophrenia. AIM: The aim of this study is to investigate the relationships between CT, depression and ASEs in schizophrenia. METHOD: ASEs were assessed in 55 patients in the early treated phases of schizophrenia using the Examination of Anomalous Self-Experience (EASE) instrument. Data on CT were collected using the Childhood Trauma Questionnaire, short form (CTQ-SF). This consists of 5 subscales: physical abuse, sexual abuse, emotional abuse, emotional neglect, and physical neglect. Assessment of depression was based on the Calgary Depression Scale for Schizophrenia (CDSS). RESULTS: We found significant associations between EASE total score and CTQ total score and between EASE total score and emotional neglect subscore in women, but not men. We also found significant associations between CDSS total score and CTQ total score and between CDSS total score and emotional abuse, emotional neglect, and physical neglect subscores in women, but not men. In men we did not find any significant associations between EASE total score, CDSS total score and any CTQ scores. CONCLUSION: CT was significantly associated with higher levels of ASEs in women in the early treated phases of schizophrenia, but not in men. This again associated with an increase in depressive symptoms.
BACKGROUND: Anomalous self-experiences (ASEs) are viewed as core features of schizophrenia. Childhood trauma (CT) has been postulated as a risk factor for developing schizophrenia. AIM: The aim of this study is to investigate the relationships between CT, depression and ASEs in schizophrenia. METHOD:ASEs were assessed in 55 patients in the early treated phases of schizophrenia using the Examination of Anomalous Self-Experience (EASE) instrument. Data on CT were collected using the Childhood Trauma Questionnaire, short form (CTQ-SF). This consists of 5 subscales: physical abuse, sexual abuse, emotional abuse, emotional neglect, and physical neglect. Assessment of depression was based on the Calgary Depression Scale for Schizophrenia (CDSS). RESULTS: We found significant associations between EASE total score and CTQ total score and between EASE total score and emotional neglect subscore in women, but not men. We also found significant associations between CDSS total score and CTQ total score and between CDSS total score and emotional abuse, emotional neglect, and physical neglect subscores in women, but not men. In men we did not find any significant associations between EASE total score, CDSS total score and any CTQ scores. CONCLUSION: CT was significantly associated with higher levels of ASEs in women in the early treated phases of schizophrenia, but not in men. This again associated with an increase in depressive symptoms.
Authors: Peter T Nelson; Gregory A Jicha; Wang-Xia Wang; Eseosa Ighodaro; Sergey Artiushin; Colin G Nichols; David W Fardo Journal: Ageing Res Rev Date: 2015-07-28 Impact factor: 10.895
Authors: Julie Nordgaard; Mads Gram Henriksen; Lennart Jansson; Peter Handest; Paul Møller; Andreas Rosen Rasmussen; Karl Erik Sandsten; Lars Siersbæk Nilsson; Maja Zandersen; Dan Zahavi; Josef Parnas Journal: Psychopathology Date: 2021-08-12 Impact factor: 1.944
Authors: Elisabeth Haug; Merete G Øie; Ole A Andreassen; Unni Bratlien; Kristin L Romm; Paul Møller; Ingrid Melle Journal: Front Hum Neurosci Date: 2016-11-07 Impact factor: 3.169
Authors: A Owoso; S Jansen; D M Ndetei; A Musau; V N Mutiso; C Mudenge; A Ngirababyeyi; A Gasovya; D Mamah Journal: Epidemiol Psychiatr Sci Date: 2017-01-26 Impact factor: 6.892
Authors: Angelina Weitkämper; Michael Kellner; Jona Ruben Iffland; Martin Driessen; Hanna Kley; Frank Neuner; Benjamin Iffland Journal: Front Psychiatry Date: 2021-07-06 Impact factor: 4.157
Authors: Monica Aas; Ole A Andreassen; Sofie R Aminoff; Ann Færden; Kristin L Romm; Ragnar Nesvåg; Akiah O Berg; Carmen Simonsen; Ingrid Agartz; Ingrid Melle Journal: BMC Psychiatry Date: 2016-05-04 Impact factor: 3.630