| Literature DB >> 25458006 |
Abstract
Mitotic cell rounding is accompanied by changes in the actin cytoskeleton, de-adhesion, and an increase in cortical rigidity. In this issue, Marchesi et al. (2014) describe an adhesion-dependent mitotic checkpoint and identify DEPDC1B as the factor responsible for coordinating de-adhesion with the ability of cells to enter mitosis.Entities:
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Year: 2014 PMID： 25458006 DOI： 10.1016/j.devcel.2014.11.008
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270