Literature DB >> 25457620

miRNAs as biomarkers of myocardial infarction: a step forward towards personalized medicine?

Emeline Goretti1, Daniel R Wagner2, Yvan Devaux3.   

Abstract

miRNAs are small noncoding RNAs known to post-transcriptionally regulate gene expression. miRNAs are expressed in the heart where they regulate multiple pathophysiological processes. The discovery of stable cardiac miRNAs in the bloodstream has also motivated the investigation of their potential as biomarkers. This review gathers the current knowledge on the use of miRNAs as novel biomarkers to improve risk stratification, diagnosis, and prognosis of patients with myocardial infarction. In the rapidly evolving era of biomarkers, the potential of miRNAs as promising tools to move personalized medicine a step forward is discussed.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  biomarker; miRNAs; myocardial infarction; personalized medicine; therapeutic targets

Mesh：

Substances：

Year:  2014        PMID： 25457620     DOI： 10.1016/j.molmed.2014.10.006

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  29 in total

Review 1.  Long noncoding RNAs in cardiac development and ageing.

Authors:  Yvan Devaux; Jennifer Zangrando; Blanche Schroen; Esther E Creemers; Thierry Pedrazzini; Ching-Pin Chang; Gerald W Dorn; Thomas Thum; Stephane Heymans
Journal:  Nat Rev Cardiol       Date:  2015-04-07       Impact factor: 32.419

2.  Which future for circulating microRNAs as biomarkers of acute myocardial infarction?

Authors:  Emeline Goretti; Yvan Devaux
Journal:  Ann Transl Med       Date:  2016-11

Review 3.  Ischemia/Reperfusion.

Authors:  Theodore Kalogeris; Christopher P Baines; Maike Krenz; Ronald J Korthuis
Journal:  Compr Physiol       Date:  2016-12-06       Impact factor: 9.090

Review 4.  Epigenetic regulation in heart failure.

Authors:  Soo Young Kim; Cyndi R Morales; Thomas G Gillette; Joseph A Hill
Journal:  Curr Opin Cardiol       Date:  2016-05       Impact factor: 2.161

Review 5.  Epigenetics and Cardiovascular Disease in Diabetes.

Authors:  Jennifer Pasquier; Jessica Hoarau-Véchot; Khalid Fakhro; Arash Rafii; Charbel Abi Khalil
Journal:  Curr Diab Rep       Date:  2015-12       Impact factor: 4.810

Review 6.  Personalized medicine in thrombosis: back to the future.

Authors:  Srikanth Nagalla; Paul F Bray
Journal:  Blood       Date:  2016-02-04       Impact factor: 22.113

7.  Incremental Value of Circulating MiR-122-5p to Predict Outcome after Out of Hospital Cardiac Arrest.

Authors:  Yvan Devaux; Antonio Salgado-Somoza; Josef Dankiewicz; Adeline Boileau; Pascal Stammet; Anna Schritz; Lu Zhang; Mélanie Vausort; Patrik Gilje; David Erlinge; Christian Hassager; Matthew P Wise; Michael Kuiper; Hans Friberg; Niklas Nielsen
Journal:  Theranostics       Date:  2017-06-25       Impact factor: 11.556

8.  MicroRNA-98 negatively regulates myocardial infarction-induced apoptosis by down-regulating Fas and caspase-3.

Authors:  Chuan Sun; Huibin Liu; Jing Guo; Yang Yu; Di Yang; Fang He; Zhimin Du
Journal:  Sci Rep       Date:  2017-08-07       Impact factor: 4.379

9.  Circulating microRNAs and Outcome in Patients with Acute Heart Failure.

Authors:  Marie-France Seronde; Mélanie Vausort; Etienne Gayat; Emeline Goretti; Leong L Ng; Iain B Squire; Nicolas Vodovar; Malha Sadoune; Jane-Lise Samuel; Thomas Thum; Alain Cohen Solal; Said Laribi; Patrick Plaisance; Daniel R Wagner; Alexandre Mebazaa; Yvan Devaux
Journal:  PLoS One       Date:  2015-11-18       Impact factor: 3.240

Review 10.  Long Noncoding RNA: Recent Updates in Atherosclerosis.

Authors:  Hao Li; Hongming Zhu; Junbo Ge
Journal:  Int J Biol Sci       Date:  2016-06-07       Impact factor: 6.580
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