| Literature DB >> 25457485 |
XingRong Peng1, JieQing Liu2, JianJun Xia2, CuiFang Wang2, XuYang Li1, YuanYuan Deng1, NiMan Bao1, ZhiRun Zhang2, MingHua Qiu3.
Abstract
Chemical investigation of the fruiting bodies of Ganoderma hainanense resulted in isolation of fourteen lanostane triterpenoids, including nine ganoderma acids and five ganoderma alcohols, together with five known compounds. Structural elucidation was determined using extensive spectroscopic technologies, Mosher's method and X-ray single crystal diffraction. Three of the compounds showed inhibitory activities against HL-60, SMMC-7721, A-549 and MCF-7 cells with IC50 values of 15.0-40.0 μM.Entities:
Keywords: Cytotoxicity; Ganoderma hainanense; Lanostane triterpenoids; Mosher’s method; X-ray diffraction
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Year: 2014 PMID： 25457485 DOI： 10.1016/j.phytochem.2014.10.009
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072