Anthony L Estrera1, Harleen K Sandhu2, Samuel S Leake2, Kristofer M Charlton-Ouw2, Rana O Afifi2, Charles C Miller2, Hazim J Safi2. 1. Department of Cardiothoracic and Vascular Surgery, Clinical Science Program, The University of Texas Medical School at Houston, and Memorial Hermann Hospital, Houston, Tex. Electronic address: Anthony.L.Estrera@uth.tmc.edu. 2. Department of Cardiothoracic and Vascular Surgery, Clinical Science Program, The University of Texas Medical School at Houston, and Memorial Hermann Hospital, Houston, Tex.
Abstract
INTRODUCTION: Controversy remains regarding management of acute type A dissection with intramural hematoma (IMH). Our purpose was to analyze our experience and report outcomes after repair of acute type A aortic dissection with IMH. METHODS: We analyzed all patients from a single center who underwent open repair for acute type A aortic dissection with IMH. RESULTS: Between 2000 and 2013, we performed 418 repairs for acute type A aortic dissection. These were divided into 2 groups of patients: 64 patients (15%) with type A IMH and 354 patients (85%) with typical dissection. Those with IMH were older (62.4 ± 13.9 years vs 56.7 ± 14.7 years; P < .0046) and presented with reduced renal function (ie, glomerular filtration rate) (P < .0341), less frequently with distal malperfusion, and less frequently with rupture (P < .0116). With IMH, the time from presentation to repair was, by strategy, longer (median, 67 vs 6 hours; P < .0001), but no mortality occurred within 3 days of presentation. Mortality with IMH did not differ from typical dissection: 7 out of 64 patients (10.9%) versus 52 out of 354 patients (14.7%; P = .4276). A lower incidence of postoperative dialysis in the IMH group approached significance: 6 out of 63 patients (9.5%) versus 64 out of 347 patients (18.4%; P = .0820). When adjusted for age and renal function, late survival was improved with IMH (P < .0343). CONCLUSIONS: Repair of acute type A aortic dissection with IMH is associated with significant early morbidity and mortality, differing minimally from typical aortic dissection. Although expectant repair within 3 days may be applied, the purposeful delay imparted little advantage. Improved late outcomes may be seen with IMH, but continued long-term surveillance is required for verification. Published by Elsevier Inc.
INTRODUCTION: Controversy remains regarding management of acute type A dissection with intramural hematoma (IMH). Our purpose was to analyze our experience and report outcomes after repair of acute type A aortic dissection with IMH. METHODS: We analyzed all patients from a single center who underwent open repair for acute type A aortic dissection with IMH. RESULTS: Between 2000 and 2013, we performed 418 repairs for acute type A aortic dissection. These were divided into 2 groups of patients: 64 patients (15%) with type A IMH and 354 patients (85%) with typical dissection. Those with IMH were older (62.4 ± 13.9 years vs 56.7 ± 14.7 years; P < .0046) and presented with reduced renal function (ie, glomerular filtration rate) (P < .0341), less frequently with distal malperfusion, and less frequently with rupture (P < .0116). With IMH, the time from presentation to repair was, by strategy, longer (median, 67 vs 6 hours; P < .0001), but no mortality occurred within 3 days of presentation. Mortality with IMH did not differ from typical dissection: 7 out of 64 patients (10.9%) versus 52 out of 354 patients (14.7%; P = .4276). A lower incidence of postoperative dialysis in the IMH group approached significance: 6 out of 63 patients (9.5%) versus 64 out of 347 patients (18.4%; P = .0820). When adjusted for age and renal function, late survival was improved with IMH (P < .0343). CONCLUSIONS: Repair of acute type A aortic dissection with IMH is associated with significant early morbidity and mortality, differing minimally from typical aortic dissection. Although expectant repair within 3 days may be applied, the purposeful delay imparted little advantage. Improved late outcomes may be seen with IMH, but continued long-term surveillance is required for verification. Published by Elsevier Inc.
Authors: Nandini M Meyersohn; Khristine Ghemigian; Michael D Shapiro; Shimoli V Shah; Brian B Ghoshhajra; Maros Ferencik Journal: Curr Treat Options Cardiovasc Med Date: 2015-08
Authors: William C Frankel; Scott A Weldon; Susan Y Green; Hiruni S Amarasekara; Scott A LeMaire; Joseph S Coselli Journal: Tex Heart Inst J Date: 2020-08-01
Authors: Harleen K Sandhu; Akiko Tanaka; Kristofer M Charlton-Ouw; Rana O Afifi; Charles C Miller; Hazim J Safi; Anthony L Estrera Journal: Ann Cardiothorac Surg Date: 2016-07
Authors: Elizabeth L Norton; David M Williams; Karen M Kim; Xiaoting Wu; Minhaj S Khaja; Himanshu J Patel; G Michael Deeb; Bo Yang Journal: Ann Cardiothorac Surg Date: 2019-09