Literature DB >> 2545451

A trial of RIT-4237 rotavirus vaccine in 1-month-old infants.

I D Mutz1, F Krainer, J Deutsch, C Kunz, D E Teuwen.   

Abstract

In a double blind placebo-controlled study rotavirus vaccine RIT 4237 was offered to young infants after the fourth week of life. The vaccine was very well tolerated. Fifty-seven out of 100 vaccine recipients and 10 out of 103 placebo recipients developed rotavirus-IgM-antibodies during the 1 month follow-up period. During a 6 month follow-up, stool samples from 2 out of 12 vaccinees and from 5 out of 12 placebo recipients contained rotavirus.

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Year:  1989        PMID: 2545451     DOI: 10.1007/BF00441518

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  16 in total

Review 1.  Perspective on the development and deployment of rotavirus vaccines.

Authors:  R Edelman
Journal:  Pediatr Infect Dis J       Date:  1987-08       Impact factor: 2.129

2.  Dose-response study of RIT 4237 oral rotavirus vaccine in breast-fed and formula-fed infants.

Authors:  T Vesikari; T Ruuska; H Bogaerts; A Delem; F André
Journal:  Pediatr Infect Dis       Date:  1985 Nov-Dec

3.  [Rotavirus infections in children (author's transl)].

Authors:  H C Dominick; G Maass
Journal:  Klin Padiatr       Date:  1979-01       Impact factor: 1.349

4.  Virus particles in epithelial cells of duodenal mucosa from children with acute non-bacterial gastroenteritis.

Authors:  R F Bishop; G P Davidson; I H Holmes; B J Ruck
Journal:  Lancet       Date:  1973-12-08       Impact factor: 79.321

5.  Increased "take" rate of oral rotavirus vaccine in infants after milk feeding.

Authors:  T Vesikari; E Isolauri; E D'Hondt; A Delem; F E André
Journal:  Lancet       Date:  1984-09-22       Impact factor: 79.321

6.  Detection of serum antibody responses to RIT 4237 rotavirus vaccine by ELISA and neutralization assays.

Authors:  A Delem; T Vesikari
Journal:  J Med Virol       Date:  1987-03       Impact factor: 2.327

7.  Immunogenicity and reactogenicity of lowered doses of rhesus rotavirus vaccine strain MMU 18006 in young children.

Authors:  M B Rennels; G A Losonsky; C L Shindledecker; T P Hughes; A Z Kapikian; M M Levine
Journal:  Pediatr Infect Dis J       Date:  1987-03       Impact factor: 2.129

8.  Clinical efficacy of the RIT 4237 live attenuated bovine rotavirus vaccine in infants vaccinated before a rotavirus epidemic.

Authors:  T Vesikari; E Isolauri; A Delem; E d'Hondt; F E André; G M Beards; T H Flewett
Journal:  J Pediatr       Date:  1985-08       Impact factor: 4.406

9.  Protection against severe rotavirus diarrhoea by rhesus rotavirus vaccine in Venezuelan infants.

Authors:  J Flores; I Perez-Schael; M Gonzalez; D Garcia; M Perez; N Daoud; W Cunto; R M Chanock; A Z Kapikian
Journal:  Lancet       Date:  1987-04-18       Impact factor: 79.321

10.  Immunogenicity and safety of live oral attenuated bovine rotavirus vaccine strain RIT 4237 in adults and young children.

Authors:  T Vesikari; E Isolauri; A Delem; E D'Hondt; F E André; G Zissis
Journal:  Lancet       Date:  1983-10-08       Impact factor: 79.321

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