Literature DB >> 25453880

Aortic hemodynamics after thoracic endovascular aortic repair, with particular attention to the bird-beak configuration.

Guido H W van Bogerijen1, Ferdinando Auricchio, Michele Conti, Adrien Lefieux, Alessandro Reali, Alessandro Veneziani, Jip L Tolenaar, Frans L Moll, Vincenzo Rampoldi, Santi Trimarchi.   

Abstract

PURPOSE: To quantitatively evaluate the impact of thoracic endovascular aortic repair (TEVAR) on aortic hemodynamics, focusing on the implications of a bird-beak configuration.
METHODS: Pre- and postoperative CTA images from a patient treated with TEVAR for post-dissecting thoracic aortic aneurysm were used to evaluate the anatomical changes induced by the stent-graft and to generate the computational network essential for computational fluid dynamics (CFD) analysis. These analyses focused on the bird-beak configuration, flow distribution into the supra-aortic branches, and narrowing of the distal descending thoracic aorta. Three different CFD analyses (A: preoperative lumen, B: postoperative lumen, and C: postoperative lumen computed without stenosis) were compared at 3 time points during the cardiac cycle (maximum acceleration of blood flow, systolic peak, and maximum deceleration of blood flow).
RESULTS: Postoperatively, disturbance of flow was reduced at the bird-beak location due to boundary conditions and change of geometry after TEVAR. Stent-graft protrusion with partial coverage of the origin of the left subclavian artery produced a disturbance of flow in this vessel. Strong velocity increase and flow disturbance were found at the aortic narrowing in the descending thoracic aorta when comparing B and C, while no effect was seen on aortic arch hemodynamics.
CONCLUSION: CFD may help physicians to understand aortic hemodynamic changes after TEVAR, including the change in aortic arch geometry, the effects of a bird-beak configuration, the supra-aortic flow distribution, and the aortic true lumen dynamics. This study is the first step in establishing a computational framework that, when completed with patient-specific data, will allow us to study thoracic aortic pathologies and their endovascular management.

Entities:  

Keywords:  aorta; biomechanics; bird-beak; computational fluid dynamics; flow disturbance; stent-graft; thoracic endovascular aortic repair; true lumen narrowing

Mesh:

Year:  2014        PMID: 25453880     DOI: 10.1583/14-4778MR.1

Source DB:  PubMed          Journal:  J Endovasc Ther        ISSN: 1526-6028            Impact factor:   3.487


  2 in total

1.  Activities at Thoracic Aortic Research Center, IRCCS Policlinico San Donato.

Authors:  Santi Trimarchi; Arnoud Kamman; Chiara Lomazzi; Sara Segreti; Marta Cova; Carlo De Vincentiis; Alessandro Frigiola; Lorenzo Menicanti; Massimiliano M Marrocco-Trischitta; Viviana Grassi; Simone Morganti; Michele Conti; Ferdinando Auricchio; Vincenzo Rampoldi
Journal:  Eur Heart J Suppl       Date:  2016-04-29       Impact factor: 1.803

2.  Identification of geometric and mechanical factors predictive of bird-beak configuration in thoracic endovascular aortic repair using computational models of stent graft deployment.

Authors:  Negin Shahbazian; David A Romero; Thomas L Forbes; Cristina H Amon
Journal:  JVS Vasc Sci       Date:  2022-06-24
  2 in total

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