Literature DB >> 2545306

Chronic septal lesions cause upregulation of cholinergic but not noradrenergic hippocampal phosphoinositide hydrolysis.

D J Connor1, L E Harrell.   

Abstract

The functional integrity of hippocampal muscarinic and noradrenergic receptors was assessed utilizing phosphatidyl inositol (PI) hydrolysis. Four months following septal lesions an enhanced hippocampal PI response to carbachol stimulation (61%) was observed while no effect was found in maximal noradrenergic stimulation.

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Year:  1989        PMID： 2545306     DOI： 10.1016/0006-8993(89)90736-1

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  2 in total

1.  Long term effects of septohippocampal lesions and intrahippocampal grafts on acetylcholine concentration, muscarinic stimulated formation of inositol phospholipids and electrically evoked release of neurotransmitters in the rat hippocampus.

Authors:  J C Cassel; R Jackisch; M Duschek; J M Hornsperger; M H Richards; C Kelche; G Hertting; B Will
Journal:  Exp Brain Res       Date:  1991       Impact factor: 1.972

2.  Functional reorganization of the noradrenergic system after partial fornix section: a behavioral and autoradiographic study.

Authors:  C Dyon-Laurent; S Romand; A Biegon; S Sara
Journal:  Exp Brain Res       Date:  1993       Impact factor: 1.972
  2 in total

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