Literature DB >> 25453041

Perceived misinterpretation rates in oncologic 18F-FDG PET/CT studies: a survey of referring physicians.

Dimitrios Karantanis1, Dimitrios Kalkanis2, Johannes Czernin3, Ken Herrmann4, Kelsey L Pomykala3, Trond V Bogsrud5, Rathan M Subramaniam6, Val J Lowe7, Martin S Allen-Auerbach3.   

Abstract

UNLABELLED: Because only pathologic examination can confirm the presence or absence of malignant disease in cancer patients, a certain rate of misinterpretation in any kind of imaging study is inevitable. For the accuracy of interpretation to be improved, determination of the nature, causes, and magnitude of this problem is needed. This study was designed to collect pertinent information from physicians referring patients for oncologic (18)F-FDG PET/CT.
METHODS: A total of 662 referring physicians completed an 11-question survey focused on their experience with the interpretation of oncologic (18)F-FDG PET/CT studies. The participants were oncologists (36.1%; n = 239), hematologists (14.5%; n = 96), radiation oncologists (7.4%; n = 49), surgeons (33.8%; n = 224), and other physicians (8.2%; n = 54). Questions were aimed at determining the frequency, nature, and causes of scan misinterpretations as well as potential solutions to reduce the frequency of misinterpretations.
RESULTS: Perceived misinterpretation rates ranged from 5% to 20%, according to most (59.3%) of the participants; 20.8% of respondents reported rates of less than 5%. Overinterpretation rather than underinterpretation was more frequently encountered (68.9% vs. 8.7%, respectively). Limited availability of a patient's history and limited experience of interpreters were the major contributors to this phenomenon, according to 46.8% and 26.7% of the participants, respectively. The actions most commonly suggested to reduce misinterpretation rates (multiple suggestions were possible) were the institution of multidisciplinary meetings (59.8%), the provision of adequate history when ordering an examination (37.4%), and a discussion with imaging specialists when receiving the results of the examination (38.4%).
CONCLUSION: Overinterpretation rather than underinterpretation of oncologic (18)F-FDG PET/CT studies prevails in clinical practice, according to referring physicians. Closer collaboration of imaging specialists with referring physicians through more multidisciplinary meetings, improved communication, and targeted training of interpreting physicians are actions suggested to reduce the rates of misinterpretation of oncologic (18)F-FDG PET/CT studies.
© 2014 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Entities:  

Keywords:  accuracy; false-negative results; false-positive results; overinterpretation; pitfall

Mesh:

Substances:

Year:  2014        PMID: 25453041      PMCID: PMC4324619          DOI: 10.2967/jnumed.114.145607

Source DB:  PubMed          Journal:  J Nucl Med        ISSN: 0161-5505            Impact factor:   10.057


  16 in total

1.  The new medical malpractice crisis.

Authors:  Joseph P Imperato
Journal:  N Engl J Med       Date:  2003-08-28       Impact factor: 91.245

2.  Oncologic 18F-FDG PET/CT: referring physicians' point of view.

Authors:  Dimitrios Karantanis; Dimitrios Kalkanis; Martin Allen-Auerbach; Trond Velde Bogsrud; Rathan M Subramaniam; Adam Danielson; Val J Lowe; Johannes Czernin
Journal:  J Nucl Med       Date:  2012-08-23       Impact factor: 10.057

3.  FDG PET evaluation of mucinous neoplasms: correlation of FDG uptake with histopathologic features.

Authors:  K L Berger; S A Nicholson; F Dehdashti; B A Siegel
Journal:  AJR Am J Roentgenol       Date:  2000-04       Impact factor: 3.959

4.  Accuracy of whole-body dual-modality fluorine-18-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography (FDG-PET/CT) for tumor staging in solid tumors: comparison with CT and PET.

Authors:  Gerald Antoch; Nina Saoudi; Hilmar Kuehl; Gerlinde Dahmen; Stefan P Mueller; Thomas Beyer; Andreas Bockisch; Jörg F Debatin; Lutz S Freudenberg
Journal:  J Clin Oncol       Date:  2004-11-01       Impact factor: 44.544

5.  Focal FDG uptake in mediastinal brown fat mimicking malignancy: a potential pitfall resolved on PET/CT.

Authors:  Mylene T Truong; Jeremy J Erasmus; Reginald F Munden; Edith M Marom; Bradley S Sabloff; Gregory W Gladish; Donald A Podoloff; Homer A Macapinlac
Journal:  AJR Am J Roentgenol       Date:  2004-10       Impact factor: 3.959

6.  Impact of positron emission tomography/computed tomography and positron emission tomography (PET) alone on expected management of patients with cancer: initial results from the National Oncologic PET Registry.

Authors:  Bruce E Hillner; Barry A Siegel; Dawei Liu; Anthony F Shields; Ilana F Gareen; Lucy Hanna; Sharon Hartson Stine; R Edward Coleman
Journal:  J Clin Oncol       Date:  2008-03-24       Impact factor: 44.544

7.  Increased (18)F-fluorodeoxyglucose uptake in benign, nonphysiologic lesions found on whole-body positron emission tomography/computed tomography (PET/CT): accumulated data from four years of experience with PET/CT.

Authors:  Ur Metser; Einat Even-Sapir
Journal:  Semin Nucl Med       Date:  2007-05       Impact factor: 4.446

Review 8.  NCCN task force: clinical utility of PET in a variety of tumor types.

Authors:  Donald A Podoloff; Douglas W Ball; Edgar Ben-Josef; Al B Benson; Steven J Cohen; R Edward Coleman; Dominique Delbeke; Maria Ho; David H Ilson; Gregory P Kalemkerian; Richard J Lee; Jay S Loeffler; Homer A Macapinlac; Robert J Morgan; Barry Alan Siegel; Seema Singhal; Douglas S Tyler; Richard J Wong
Journal:  J Natl Compr Canc Netw       Date:  2009-06       Impact factor: 11.908

9.  Causes and imaging features of false positives and false negatives on F-PET/CT in oncologic imaging.

Authors:  Niamh M Long; Clare S Smith
Journal:  Insights Imaging       Date:  2011-09-09

Review 10.  False positive and false negative FDG-PET scans in various thoracic diseases.

Authors:  Jung Min Chang; Hyun Ju Lee; Jin Mo Goo; Ho-Young Lee; Jong Jin Lee; June-Key Chung; Jung-Gi Im
Journal:  Korean J Radiol       Date:  2006 Jan-Mar       Impact factor: 3.500

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  1 in total

Review 1.  Physician centred imaging interpretation is dying out - why should I be a nuclear medicine physician?

Authors:  Roland Hustinx
Journal:  Eur J Nucl Med Mol Imaging       Date:  2019-06-07       Impact factor: 9.236

  1 in total

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