Literature DB >> 25451319

The emerging roles of microRNAs in cancer metabolism.

Brian Chan1, Jacob Manley, Jae Lee, Shree Ram Singh.   

Abstract

The major goal of cancer therapy is to destroy cancer cells without harming normal cells. However, because cancer cells have incredible heterogeneity and adaptability, it is difficult to target them therapeutically. Metabolic reprogramming has emerged as a common feature of cancer. Ever since microRNAs (miRNAs) have been found to influence metabolism, researchers have been trying to address the connection between cancer cells and specific miRNAs. Many of the well-known miRNAs relate to crucial genes that can impact metabolic pathways, both negatively and positively. With a better understanding of how different pathways are affected, the roles of miRNAs will be more transparent, which could lead to the discovery of new ideas about the concept of tumorigenesis and other cancer-related topics.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

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Year:  2015        PMID: 25451319     DOI: 10.1016/j.canlet.2014.10.011

Source DB:  PubMed          Journal:  Cancer Lett        ISSN: 0304-3835            Impact factor:   8.679


  39 in total

1.  A tumor-suppressive microRNA, miRNA-485-5p, inhibits glioma cell proliferation and invasion by down-regulating TPD52L2.

Authors:  Jin Yu; Shi-Wen Wu; Wei-Ping Wu
Journal:  Am J Transl Res       Date:  2017-07-15       Impact factor: 4.060

2.  Deep sequencing reveals microRNA signature is altered in the rat epididymis following bilateral castration.

Authors:  Yan Li; Haiyan Wang; Yangmei Qin; Juan Liu; Ning Li; Zhiliang Ji; Jianyuan Li
Journal:  Genes Genomics       Date:  2019-03-11       Impact factor: 1.839

3.  Serum miR-21 level: a potential diagnostic and prognostic biomarker for non-small cell lung cancer.

Authors:  Wei Zhao; Jun-Jie Zhao; Long Zhang; Qin-Fu Xu; Yu-Miao Zhao; Xiao-Ya Shi; Ai-Guo Xu
Journal:  Int J Clin Exp Med       Date:  2015-09-15

Review 4.  MicroRNA aberrations: An emerging field for gallbladder cancer management.

Authors:  Vishal Chandra; Jong Joo Kim; Balraj Mittal; Rajani Rai
Journal:  World J Gastroenterol       Date:  2016-02-07       Impact factor: 5.742

Review 5.  Long non-coding RNAs in cancer metabolism.

Authors:  Zhen-Dong Xiao; Li Zhuang; Boyi Gan
Journal:  Bioessays       Date:  2016-08-23       Impact factor: 4.345

6.  MiR-570 inhibited the cell proliferation and invasion through directly targeting B7-H1 in hepatocellular carcinoma.

Authors:  Wei Guo; Wei Tan; Shan Liu; Xuhui Huang; Juze Lin; Ronghua Liang; Le Su; Qiao Su; Changjun Wang
Journal:  Tumour Biol       Date:  2015-06-18

7.  Shikonin, vitamin K3 and vitamin K5 inhibit multiple glycolytic enzymes in MCF-7 cells.

Authors:  Jing Chen; Xun Hu; Jingjie Cui
Journal:  Oncol Lett       Date:  2018-03-13       Impact factor: 2.967

8.  MicroRNA-299-3p promotes the sensibility of lung cancer to doxorubicin through directly targeting ABCE1.

Authors:  Dawei Zheng; Yan Dai; Song Wang; Xiaoyu Xing
Journal:  Int J Clin Exp Pathol       Date:  2015-09-01

9.  Low MiR-149 expression is associated with unfavorable prognosis and enhanced Akt/mTOR signaling in glioma.

Authors:  Liang Xue; Yi Wang; Shuyuan Yue; Jianning Zhang
Journal:  Int J Clin Exp Pathol       Date:  2015-09-01

10.  MicroRNA-153 acts as a prognostic marker in gastric cancer and its role in cell migration and invasion.

Authors:  Zhengliang Zhang; Jiangli Sun; Zhenghai Bai; Haijun Li; Shicai He; Rui Chen; Xiangming Che
Journal:  Onco Targets Ther       Date:  2015-02-02       Impact factor: 4.147

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