Literature DB >> 25451139

CNS involvement in pancreatic adenocarcinoma: a report of eight cases from the Johns Hopkins Hospital and review of literature.

Abhijeet Kumar1, Meenakshi Dagar, Joseph Herman, Christine Iacobuzio-Donahue, Dan Laheru.   

Abstract

PURPOSE: CNS metastasis of pancreatic cancer is extremely rare, although systemic metastasis is very common. We present eight such cases with various forms of nervous system involvement.
METHODS: Data was gathered from chart review of 800 patients with pancreatic cancer treated between 2004 and 2012 of which eight patients are described with CNS metastases.
RESULTS: The median age of patients was 61.5 years and the median time to develop CNS metastasis was 29 months. Interestingly, two patients had no other sites of metastasis. The treatment modalities tried included resection followed by radiation, resection alone, or whole brain radiation.

Entities:  

Mesh:

Year:  2015        PMID: 25451139      PMCID: PMC4451956          DOI: 10.1007/s12029-014-9667-y

Source DB:  PubMed          Journal:  J Gastrointest Cancer


  22 in total

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5.  Calcified brain metastases from acinar-cell carcinoma of pancreas.

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Review 7.  Gastrointestinal cancer and brain metastasis: a rare and ominous sign.

Authors:  Pauline H Go; Zachary Klaassen; Michael C Meadows; Ronald S Chamberlain
Journal:  Cancer       Date:  2011-02-11       Impact factor: 6.860

8.  Brain and skull metastases of hepatic or pancreatic cancer--report of six cases.

Authors:  J Kuratsu; M Murakami; S Uemura; Y Ushio
Journal:  Neurol Med Chir (Tokyo)       Date:  1990-07       Impact factor: 1.742

9.  Brain metastasis from malignant pancreatic somatostatinoma. Case report.

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Journal:  J Neurosurg       Date:  1996-10       Impact factor: 5.115

10.  Consensus transcriptome signature of perineural invasion in pancreatic carcinoma.

Authors:  Ivane Abiatari; Tiago DeOliveira; Vachtang Kerkadze; Christian Schwager; Irene Esposito; Nathalia A Giese; Peter Huber; Frank Bergman; Amir Abdollahi; Helmut Friess; Jörg Kleeff
Journal:  Mol Cancer Ther       Date:  2009-06-09       Impact factor: 6.261

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  8 in total

Review 1.  Gamma Knife treatment of recurrent CNS metastases of pancreatic origin: a case report and review of the literature.

Authors:  Subha Perni; Tony J Wang; Jerry Lesser; Christopher Mandigo; Steven R Isaacson; David P Horowitz
Journal:  CNS Oncol       Date:  2017-04

2.  A case report of microsatellite instability (MSI)-high, HER2 amplified pancreatic adenocarcinoma with central nervous system metastasis.

Authors:  Nicholas C DeVito; Colm Kelleher; Kyle C Strickland; James Abbruzzese; Carey Anders; Brent A Hanks; Jingquan Jia; Niharika B Mettu; Michael A Morse; Margot O'Neill; Hope Uronis; Yousuf Zafar; John H Strickler
Journal:  AME Case Rep       Date:  2021-04-25

3.  Prognostic value of site-specific metastases in pancreatic adenocarcinoma: A Surveillance Epidemiology and End Results database analysis.

Authors:  Hani Oweira; Ulf Petrausch; Daniel Helbling; Jan Schmidt; Meinrad Mannhart; Arianeb Mehrabi; Othmar Schöb; Anwar Giryes; Michael Decker; Omar Abdel-Rahman
Journal:  World J Gastroenterol       Date:  2017-03-14       Impact factor: 5.742

4.  Validation of the graded prognostic assessment for gastrointestinal cancers with brain metastases (GI-GPA).

Authors:  Carsten Nieder; Mandy Hintz; Ilinca Popp; Angelika Bilger; Anca L Grosu
Journal:  Radiat Oncol       Date:  2020-02-13       Impact factor: 3.481

Review 5.  Simultaneous brain and lung metastases of pancreatic ductal adenocarcinoma after curative pancreatectomy: a case report and literature review.

Authors:  Yoshito Oka; Shigetsugu Takano; Yusuke Kouchi; Katsunori Furukawa; Tsukasa Takayashiki; Satoshi Kuboki; Daisuke Suzuki; Nozomu Sakai; Shingo Kagawa; Isamu Hosokawa; Takashi Mishima; Takanori Konishi; Takashi Kishimoto; Masayuki Ohtsuka
Journal:  BMC Gastroenterol       Date:  2021-01-06       Impact factor: 3.067

6.  Late metachronous cerebral metastasis of pancreatic adenocarcinoma of the tail of the pancreas: a case report.

Authors:  Kyriakos Papadimitriou; Daniel Kiss-Bodolay; Abderrahmane Hedjoudje; Diego San Millan; Alexandre Simonin; Jean-Yves Fournier; Karen Huscher
Journal:  J Med Case Rep       Date:  2022-04-04

7.  A Rare Case of Brain Metastases in an Elderly Patient With Primary Pancreatic Cancer.

Authors:  Sharad Rajpal; Hash B Taha; Lukas Kvascevicius; Sigita Burneikiene
Journal:  Cureus       Date:  2022-08-01

8.  Brain metastasis in pancreatic cancer: Two case reports.

Authors:  Takashi Sasaki; Tatsuya Sato; Yousuke Nakai; Naoki Sasahira; Hiroyuki Isayama; Kazuhiko Koike
Journal:  Medicine (Baltimore)       Date:  2019-01       Impact factor: 1.817

  8 in total

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