B Hannache1, A Boutefnouchet2, D Bazin3, M Daudon4, E Foy5, S Rouzière6, A Dahdouh7. 1. Faculté des sciences de la nature et de vie, université Constantine-1, 25017 Constantine, Algérie; Faculté des mathématiques et de l'informatique et des sciences de la matière, université 08 Mai 1945-Guelma, BP 401, 24000 Guelma, Algérie. 2. Laboratoire de biophysique, faculté de médecine, 23009 Annaba, Algérie. 3. CNRS-LCMCP-UPMC, collège de France, 11, place Marcelin-Berthelot, 75231 Paris cedex 05, France. 4. Service d'explorations fonctionnelles, hôpital Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France. Electronic address: Michel.daudon@tnn.aphp.fr. 5. Laboratoire P.-Süe (CEA-CNRS)-Saclay, 91191 Gif-sur-Yvette cedex, France. 6. Laboratoire de physique des solides, université Paris-XI, bâtiment 510, 91405 Orsay, France. 7. EHS d'uro-néphrologie-Daksi, 25000 Constantine, Algérie.
Abstract
AIM: To assess the possible nature and role of trace elements in the pathogenesis of urinary stones. MATERIAL AND METHOD: A series of 76 calculi from the East-Algerian region has been investigated through Fourier transform infrared spectroscopy for chemical analysis and X-ray fluorescence for detecting trace elements. RESULTS: Among the detected trace elements, Zn, Sr, Pb, Cu, Rb and Se, only the first three had significant values. Overall, the calcium components, namely calcium oxalate and calcium phosphate, were the most loaded by these elements contrary to organic components such as uric acid and cystine, which had low contents. CONCLUSION: The correlation of contents of Zn and Sr with the stone components (carbapatite, weddellite and whewellite) suggests an adsorption of these trace elements in the case of calcium stones rather than a catalytic process. LEVEL OF EVIDENCE: 3.
AIM: To assess the possible nature and role of trace elements in the pathogenesis of urinary stones. MATERIAL AND METHOD: A series of 76 calculi from the East-Algerian region has been investigated through Fourier transform infrared spectroscopy for chemical analysis and X-ray fluorescence for detecting trace elements. RESULTS: Among the detected trace elements, Zn, Sr, Pb, Cu, Rb and Se, only the first three had significant values. Overall, the calcium components, namely calcium oxalate and calcium phosphate, were the most loaded by these elements contrary to organic components such as uric acid and cystine, which had low contents. CONCLUSION: The correlation of contents of Zn and Sr with the stone components (carbapatite, weddellite and whewellite) suggests an adsorption of these trace elements in the case of calcium stones rather than a catalytic process. LEVEL OF EVIDENCE: 3.