| Literature DB >> 25449256 |
Roger Dumke1, Simone Stolz2, Enno Jacobs3, Thomas Juretzek4.
Abstract
The development of macrolide resistance that occurred during 3 days of therapy with azithromycin to treat Mycoplasma pneumoniae pneumonia in a paediatric patient is reported. After extended molecular characterization of strains, the parallel occurrence of clones showing the non-mutated wild-type 23S rRNA sequence as well as mutations A2063G and A2064G, which are both responsible for phenotypic resistance, was confirmed for the first time.Entities:
Keywords: Community-acquired pneumonia; Mycoplasma pneumoniae; Typing Macrolide resistance
Mesh:
Substances:
Year: 2014 PMID: 25449256 DOI: 10.1016/j.ijid.2014.07.014
Source DB: PubMed Journal: Int J Infect Dis ISSN: 1201-9712 Impact factor: 3.623