Literature DB >> 2544886

An apaH mutation causes AppppA to accumulate and affects motility and catabolite repression in Escherichia coli.

S B Farr1, D N Arnosti, M J Chamberlin, B N Ames.   

Abstract

apaH- mutants lack the hydrolase responsible for degradation of AppppN dinucleotides in Escherichia coli and show a greater than or equal to 16-fold increase in AppppA under nonstress conditions. These mutants lack detectable activity of sigma F, a factor required for transcription of motility and chemotaxis genes. Expression of the flbB/flaI operon, thought to encode sigma F, is decreased in apaH- mutants, and there appears to be a general decrease in expression of genes regulated by cAMP-binding protein and cAMP as well.

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Year:  1989        PMID： 2544886      PMCID： PMC297546          DOI： 10.1073/pnas.86.13.5010

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  36 in total

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Journal:  Bacteriol Rev       Date:  1972-12

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Journal:  Anal Biochem       Date:  1972-01       Impact factor: 3.365

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Authors:  K McKenney; H Shimatake; D Court; U Schmeissner; C Brady; M Rosenberg
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Authors:  J C Stephens; S W Artz; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1975-11       Impact factor: 11.205

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Authors:  M Silverman; M Simon
Journal:  J Bacteriol       Date:  1974-12       Impact factor: 3.490

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Authors:  T Yokota; J S Gots
Journal:  J Bacteriol       Date:  1970-08       Impact factor: 3.490
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  33 in total

Review 1.  Cyclic AMP in prokaryotes.

Authors:  J L Botsford; J G Harman
Journal:  Microbiol Rev       Date:  1992-03

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Authors:  M K Berlyn
Journal:  Microbiol Mol Biol Rev       Date:  1998-09       Impact factor: 11.056

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7.  Legionella pneumophila NudA Is a Nudix hydrolase and virulence factor.

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8.  Anti-dormant mycobacterial activity and target molecule of melophlins, tetramic acid derivatives isolated from a marine sponge of Melophlus sp.

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Journal:  J Nat Med       Date:  2016-05-19       Impact factor: 2.343

9.  The green alga Scenedesmus obliquus contains both diadenosine 5',5'''-P1,P4-tetraphosphate (asymmetrical) pyrophosphohydrolase and phosphorylase activities.

Authors:  A G McLennan; E Mayers; S Hankin; N M Thorne; M Prescott; R Powls
Journal:  Biochem J       Date:  1994-05-15       Impact factor: 3.857

10.  AppppA-binding protein E89 is the Escherichia coli heat shock protein ClpB.

Authors:  E K Fuge; S B Farr
Journal:  J Bacteriol       Date:  1993-04       Impact factor: 3.490
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