| Literature DB >> 25448783 |
Charlotte Wetherill1, Jonathan Sutcliffe2.
Abstract
Hirschsprung disease and Anorectal Malformations are congenital disorders presenting in neonates with distal intestinal obstruction. Hirschsprung disease is associated with a functional distal bowel obstruction resulting from the abnormal development of the enteric nervous system and ensuing aganglionosis of the distal gut. Anorectal Malformations comprise a spectrum of anatomical anomalies causing a mechanical bowel obstruction. Both conditions are frequently associated with congenital abnormalities/syndromes, which require careful assessment and evaluation. Surgical intervention is usually required for both conditions with careful preparation and meticulous technique. Long-term follow-up allows early identification and treatment of potentially debilitating symptoms, which include faecal incontinence.Entities:
Keywords: Anorectal malformation; Congenital abnormalities; Hirschsprung disease; Neonatal intestinal obstruction
Mesh:
Year: 2014 PMID: 25448783 DOI: 10.1016/j.earlhumdev.2014.09.016
Source DB: PubMed Journal: Early Hum Dev ISSN: 0378-3782 Impact factor: 2.079