Purun Lei1, Jiafeng Fang1, Yong Huang1, Zongheng Zheng1, Bo Wei1, Hongbo Wei2. 1. Department of Gastrointestinal Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 0086-510000, China. 2. Department of Gastrointestinal Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 0086-510000, China. Electronic address: weihbsysu@163.com.
Abstract
BACKGROUND AND AIMS: Reconstruction of digestive tract after pancreaticodudenectomy now has been proved associated with pancreatic fistula and complication incidence. The meta-analysis was conducted at the appropriate time enough randomized controlled trials were reported. METHODS: Systematically literature search was performed through PubMed, EMBASE and Cochrane Library database without restriction to regions, or languages, only randomized controlled trials was included. 7 studies compared pancreatogastrostomy with pancreaticojejunostomy were included for meta-analysis. Fixed and random-effects models were used to measure the pooled estimates. RESULTS: Patient underwent pancreatogastrostomy after pancreatoduodenectomy suffered less pancreatic fistula(p = 0.001) and bile leakage (p = 0.02), while the operative time, hospital stay, delayed gastric emptying and overall morbidity were comparable. CONCLUSION: Pancreatogastrostomy is a recommended anastomosis technique according to the meta-analysis due to minimize incidence of pancreatic fistula and bile leakage.
BACKGROUND AND AIMS: Reconstruction of digestive tract after pancreaticodudenectomy now has been proved associated with pancreatic fistula and complication incidence. The meta-analysis was conducted at the appropriate time enough randomized controlled trials were reported. METHODS: Systematically literature search was performed through PubMed, EMBASE and Cochrane Library database without restriction to regions, or languages, only randomized controlled trials was included. 7 studies compared pancreatogastrostomy with pancreaticojejunostomy were included for meta-analysis. Fixed and random-effects models were used to measure the pooled estimates. RESULTS:Patient underwent pancreatogastrostomy after pancreatoduodenectomy suffered less pancreatic fistula(p = 0.001) and bile leakage (p = 0.02), while the operative time, hospital stay, delayed gastric emptying and overall morbidity were comparable. CONCLUSION: Pancreatogastrostomy is a recommended anastomosis technique according to the meta-analysis due to minimize incidence of pancreatic fistula and bile leakage.