Literature DB >> 25448655

Is it safe the reversal of a diverting stoma during adjuvant chemotherapy in elderly rectal cancer patients?

Bong-Hyeon Kye1, Hyung-Jin Kim1, Jun-Gi Kim2, Hyeon-Min Cho3.   

Abstract

INTRODUCTION: The aim of this study was to investigate the clinical outcomes between 2 groups of elderly rectal cancer patients according to the time duration after which their diverting stoma can be reversed.
METHODS: We recruited 124 patients who were ≥65 years old and had undergone diverting stoma after rectal cancer surgery. In Group 1, the reversal of the stoma was predominantly performed after the sixth adjuvant chemotherapy. In Group 2, the reversal was predominantly performed after the third adjuvant chemotherapy.
RESULTS: The mean duration for which patients had a stoma was 28.6 ± 9.9 weeks in Group 1 and 17.1 ± 7.4 weeks in Group 2. The interval between stoma formation and stoma formation-related complications was slightly longer in Group 1 than in Group 2 (13.5 ± 9.7 vs. 8.0 ± 4.9 weeks, p = 0.075). There were 16 stoma-related complications in Group 1 (23.2%) and 10 in Group 2 (18.2%) (p = 0.516). There were 6 stoma closure-related complications in Group 1 (8.8%) and 6 in Group 2 (10.9%) (p = 0.766). DISCUSSION: This study shows that stoma closure during adjuvant chemotherapy is no more harmful than stoma closure after termination of adjuvant chemotherapy.
CONCLUSION: It may be possible to limit the duration of diverting stoma following rectal cancer surgery, even if patients are elderly and undergoing adjuvant chemotherapy.
Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Adjuvant chemotherapy; Diverting stoma; Rectal cancer; Stoma closure; Stoma-related complications

Mesh:

Year:  2014        PMID: 25448655     DOI: 10.1016/j.ijsu.2014.10.018

Source DB:  PubMed          Journal:  Int J Surg        ISSN: 1743-9159            Impact factor:   6.071


  2 in total

1.  Risk factors for the incidence and severity of peristomal skin disorders defined using two scoring systems.

Authors:  Takuya Shiraishi; Yuji Nishizawa; Mifumi Nakajima; Ryoko Kado; Koji Ikeda; Yuichiro Tsukada; Takeshi Sasaki; Masaaki Ito
Journal:  Surg Today       Date:  2019-09-11       Impact factor: 2.549

2.  Clinical Outcomes of Ileostomy Closure before Adjuvant Chemotherapy after Rectal Cancer Surgery: An Observational Study from a Chinese Center.

Authors:  Zhen Sun; Yufeng Zhao; Lu Liu; Jichao Qin
Journal:  Gastroenterol Res Pract       Date:  2021-07-13       Impact factor: 2.260

  2 in total

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