| Literature DB >> 2544829 |
A J Thompson1, C Kennard, M Swash, B Summers, G M Yuill, D I Shepherd, S Roche, G D Perkin, L A Loizou, R Ferner.
Abstract
To compare the efficacy of high-dose intravenous methylprednisolone with intramuscular ACTH in the treatment of acute relapse in multiple sclerosis, we undertook a double-blind, randomized, controlled study involving 61 patients. There was a marked improvement in both groups in the course of the study, but no difference between them in either the rate of recovery or the final outcome. High-dose IV methylprednisolone is a safe alternative to ACTH in the management of acute relapse in MS.Entities:
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Year: 1989 PMID： 2544829 DOI： 10.1212/wnl.39.7.969
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910