Literature DB >> 25447990

A modular zinc finger adaptor accelerates the covalent linkage of proteins at specific locations on DNA nanoscaffolds.

Eiji Nakata1, Huyen Dinh, Tien Anh Ngo, Masayuki Saimura, Takashi Morii.   

Abstract

A modular adaptor consisting of a sequence-specific DNA binding zinc finger protein and a self-ligating protein-tag was developed to expedite efficient formation of a covalent linkage between an individual protein molecule and the programmed address modified with a tag-substrate on the DNA nanostructure.

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Year:  2015        PMID： 25447990     DOI： 10.1039/c4cc08167f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Incorporation of native antibodies and Fc-fusion proteins on DNA nanostructures via a modular conjugation strategy.

Authors:  Bas J H M Rosier; Glenn A O Cremers; Wouter Engelen; Maarten Merkx; Luc Brunsveld; Tom F A de Greef
Journal:  Chem Commun (Camb)       Date:  2017-06-29       Impact factor: 6.222

Review 2.  Mechanistic Aspects for the Modulation of Enzyme Reactions on the DNA Scaffold.

Authors:  Peng Lin; Hui Yang; Eiji Nakata; Takashi Morii
Journal:  Molecules       Date:  2022-09-24       Impact factor: 4.927

3.  Enhanced enzymatic activity exerted by a packed assembly of a single type of enzyme.

Authors:  Huyen Dinh; Eiji Nakata; Kaori Mutsuda-Zapater; Masayuki Saimura; Masahiro Kinoshita; Takashi Morii
Journal:  Chem Sci       Date:  2020-07-27       Impact factor: 9.825

4.  Dynamic Shape Transformation of a DNA Scaffold Applied for an Enzyme Nanocarrier.

Authors:  Peng Lin; Huyen Dinh; Eiji Nakata; Takashi Morii
Journal:  Front Chem       Date:  2021-06-24       Impact factor: 5.221

5.  Rational design of a DNA sequence-specific modular protein tag by tuning the alkylation kinetics.

Authors:  Thang Minh Nguyen; Eiji Nakata; Zhengxiao Zhang; Masayuki Saimura; Huyen Dinh; Takashi Morii
Journal:  Chem Sci       Date:  2019-08-20       Impact factor: 9.825
  5 in total

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