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Literature DB >> 25444742

SIRT1: role in cardiovascular biology.

Abstract

SIRT1 (silent information regulator two protein) is a type III protein deacetylase that regulates a variety of important metabolic and physiologic processes including stress resistance, metabolism, apoptosis and energy balance. It reverses cholesterol transport and reduces risk for development of atherosclerosis and cardiovascular disease. The following review highlights the potential role of SIRT1 on cardiovascular biology and function.

Entities: Chemical Disease Gene

Keywords: Cardiovascular biology; Expression regulation; SIRT1; Senescence

Mesh：

Substances：

Year: 2014 PMID： 25444742 DOI： 10.1016/j.cca.2014.10.036

Source DB: PubMed Journal: Clin Chim Acta ISSN： 0009-8981 Impact factor: 3.786

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Cited

13 in total

1. Serum SIRT1 Is Associated with Frailty and Adipokines in Older Adults.

Authors: L Ma; H Niu; G Sha; Y Zhang; P Liu; Y Li
Journal: J Nutr Health Aging Date: 2019 Impact factor: 4.075

Review 2. Role of NAD⁺ and mitochondrial sirtuins in cardiac and renal diseases.

Authors: Kathleen A Hershberger; Angelical S Martin; Matthew D Hirschey
Journal: Nat Rev Nephrol Date: 2017-02-06 Impact factor: 28.314

Review 3. The protective effects of 17-β estradiol and SIRT1 against cardiac hypertrophy: a review.

Authors: Zahra Hajializadeh; Mohammad Khaksari
Journal: Heart Fail Rev Date: 2021-09-18 Impact factor: 4.214

4. Preventive Effect of Betaine Against Cognitive Impairments in Amyloid β Peptide-Injected Mice Through Sirtuin1 in Hippocampus.

Authors: Daisuke Ibi; Sari Kondo; Ayano Ohmi; Yuya Kojima; Genki Nakasai; Rika Takaba; Masayuki Hiramatsu
Journal: Neurochem Res Date: 2022-05-21 Impact factor: 4.414

5. SIRT1 rs7896005 polymorphism affects major vascular outcomes, not all-cause mortality, in Caucasians with type 2 diabetes: A 13-year observational study.

Authors: Angela Dardano; Daniela Lucchesi; Monia Garofolo; Elisa Gualdani; Pierpaolo Falcetta; Veronica Sancho Bornez; Paolo Francesconi; Stefano Del Prato; Giuseppe Penno
Journal: Diabetes Metab Res Rev Date: 2022-02-07 Impact factor: 8.128

SIRT1: role in cardiovascular biology.

1. Serum SIRT1 Is Associated with Frailty and Adipokines in Older Adults.

Review 2. Role of NAD⁺ and mitochondrial sirtuins in cardiac and renal diseases.

Review 3. The protective effects of 17-β estradiol and SIRT1 against cardiac hypertrophy: a review.

4. Preventive Effect of Betaine Against Cognitive Impairments in Amyloid β Peptide-Injected Mice Through Sirtuin1 in Hippocampus.

5. SIRT1 rs7896005 polymorphism affects major vascular outcomes, not all-cause mortality, in Caucasians with type 2 diabetes: A 13-year observational study.

6. Estrogen modulates vascular smooth muscle cell function through downregulation of SIRT1.

7. Sirtuin 1 rs1467568 and rs7895833 in South African Indians with early-onset coronary artery disease.

8. A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun.

9. Anti-Apoptotic and Pro-Survival Effect of Alpinate Oxyphyllae Fructus (AOF) in a d-Galactose-Induced Aging Heart.

10. Chikusetsu saponin IVa confers cardioprotection via SIRT1/ERK1/2 and Homer1a pathway.

Review 2. Role of NAD+ and mitochondrial sirtuins in cardiac and renal diseases.

Review 3. The protective effects of 17-β estradiol and SIRT1 against cardiac hypertrophy: a review.

Review 2. Role of NAD⁺ and mitochondrial sirtuins in cardiac and renal diseases.