Literature DB >> 25444570

The reproducibility of QTc changes after meal intake.

Jorg Taubel1, Georg Ferber2.   

Abstract

Mesh：

Year:  2014        PMID： 25444570     DOI： 10.1016/j.jelectrocard.2014.11.006

Source DB:  PubMed          Journal:  J Electrocardiol        ISSN： 0022-0736            Impact factor:   1.438


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  7 in total

Review 1.  Scientific white paper on concentration-QTc modeling.

Authors:  Christine Garnett; Peter L Bonate; Qianyu Dang; Georg Ferber; Dalong Huang; Jiang Liu; Devan Mehrotra; Steve Riley; Philip Sager; Christoffer Tornoe; Yaning Wang
Journal:  J Pharmacokinet Pharmacodyn       Date:  2017-12-05       Impact factor: 2.745

2.  Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval--A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity.

Authors:  Jörg Täubel; Georg Ferber; Ulrike Lorch; Duolao Wang; Mariano Sust; A John Camm
Journal:  PLoS One       Date:  2015-08-20       Impact factor: 3.240

3.  The Power of Phase I Studies to Detect Clinical Relevant QTc Prolongation: A Resampling Simulation Study.

Authors:  Georg Ferber; Ulrike Lorch; Jörg Täubel
Journal:  Biomed Res Int       Date:  2015-10-05       Impact factor: 3.411

4.  Use of Early Clinical Trial Data to Support Thorough QT Study Waiver for Upadacitinib and Utility of Food Effect to Demonstrate ECG Assay Sensitivity.

Authors:  Mohamed-Eslam F Mohamed; Jiewei Zeng; Ping Jiang; Balakrishna Hosmane; Ahmed A Othman
Journal:  Clin Pharmacol Ther       Date:  2017-09-25       Impact factor: 6.875

Review 5.  Evaluating cardiac risk: exposure response analysis in early clinical drug development.

Authors:  Julie Grenier; Sabina Paglialunga; Bruce H Morimoto; Robert M Lester
Journal:  Drug Healthc Patient Saf       Date:  2018-04-18

6.  Confirmation of the Cardiac Safety of PGF2α Receptor Antagonist OBE022 in a First-in-Human Study in Healthy Subjects, Using Intensive ECG Assessments.

Authors:  Jörg Täubel; Ulrike Lorch; Simon Coates; Sara Fernandes; Paul Foley; Georg Ferber; Jean-Pierre Gotteland; Oliver Pohl
Journal:  Clin Pharmacol Drug Dev       Date:  2018-02-28

7.  Concentration-QT modelling of the novel DHFR inhibitor P218 in healthy male volunteers.

Authors:  Jӧrg Täubel; Ulrike Lorch; Georg Ferber; Christopher S Spencer; Anne Freier; Simon Coates; Myriam El Gaaloul; Cristina Donini; Mohamed Farouk Chughlay; Stephan Chalon
Journal:  Br J Clin Pharmacol       Date:  2021-07-09       Impact factor: 3.716
  7 in total

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