Literature DB >> 25444530

Increased plasma incretin concentrations identifies a subset of patients with persistent congenital hyperinsulinism without KATP channel gene defects.

Yanqin Shi1, Hima B Avatapalle2, Mars S Skae2, Raja Padidela2, Melanie Newbould3, Lindsey Rigby2, Sarah E Flanagan4, Sian Ellard4, Jacques Rahier5, Peter E Clayton6, Mark J Dunne1, Indraneel Banerjee2, Karen E Cosgrove7.   

Abstract

Congenital hyperinsulinism causes profound hypoglycemia, which may persist or resolve spontaneously. Among 13 children with congenital hyperinsulinism, elevated incretin hormone concentrations were detected in 2 with atypical, persistent disease. We suggest that incretin biomarkers may identify these patients, and that elevated hormone levels may contribute to their pathophysiology.
Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 25444530     DOI： 10.1016/j.jpeds.2014.09.019

Source DB:  PubMed          Journal:  J Pediatr        ISSN： 0022-3476            Impact factor:   4.406


  7 in total

1.  Dipeptidyl peptidase-4 expression in pancreatic tissue from patients with congenital hyperinsulinism.

Authors:  Sofia A Rahman; Senthil Senniappan; Maha Sherif; Sophia Tahir; Khalid Hussain
Journal:  Int J Clin Exp Pathol       Date:  2015-07-01

2.  Atypical Forms of Congenital Hyperinsulinism in Infancy Are Associated With Mosaic Patterns of Immature Islet Cells.

Authors:  Bing Han; Zainab Mohamed; Maria Salomon Estebanez; Ross J Craigie; Melanie Newbould; Edmund Cheesman; Raja Padidela; Mars Skae; Matthew Johnson; Sarah Flanagan; Sian Ellard; Karen E Cosgrove; Indraneel Banerjee; Mark J Dunne
Journal:  J Clin Endocrinol Metab       Date:  2017-09-01       Impact factor: 5.958

Review 3.  The Role of GLP-1 Signaling in Hypoglycemia due to Hyperinsulinism.

Authors:  Melinda Danowitz; Diva D De Leon
Journal:  Front Endocrinol (Lausanne)       Date:  2022-03-24       Impact factor: 6.055

4.  Increased referrals for congenital hyperinsulinism genetic testing in children with trisomy 21 reflects the high burden of non-genetic risk factors in this group.

Authors:  Thomas I Hewat; Thomas W Laver; Jayne A L Houghton; Jonna M E Männistö; Sabah Alvi; Stephen P Brearey; Declan Cody; Antonia Dastamani; Miguel De Los Santos La Torre; Nuala Murphy; Birgit Rami-Merhar; Birgit Wefers; Hanna Huopio; Indraneel Banerjee; Matthew B Johnson; Sarah E Flanagan
Journal:  Pediatr Diabetes       Date:  2022-03-23       Impact factor: 3.409

Review 5.  Hyperinsulinemic Hypoglycemia - The Molecular Mechanisms.

Authors:  Azizun Nessa; Sofia A Rahman; Khalid Hussain
Journal:  Front Endocrinol (Lausanne)       Date:  2016-03-31       Impact factor: 5.555

6.  Enhanced Islet Cell Nucleomegaly Defines Diffuse Congenital Hyperinsulinism in Infancy but Not Other Forms of the Disease.

Authors:  Bing Han; Melanie Newbould; Gauri Batra; Edmund Cheesman; Ross J Craigie; Zainab Mohamed; Lindsey Rigby; Raja Padidela; Mars Skae; Aleksandr Mironov; Tobias Starborg; Karl E Kadler; Karen E Cosgrove; Indraneel Banerjee; Mark J Dunne
Journal:  Am J Clin Pathol       Date:  2016-06       Impact factor: 2.493

Review 7.  Hyperinsulinemic hypoglycemia in children and adolescents: Recent advances in understanding of pathophysiology and management.

Authors:  Maria Gϋemes; Sofia Asim Rahman; Ritika R Kapoor; Sarah Flanagan; Jayne A L Houghton; Shivani Misra; Nick Oliver; Mehul Tulsidas Dattani; Pratik Shah
Journal:  Rev Endocr Metab Disord       Date:  2020-12       Impact factor: 6.514
  7 in total

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