| Literature DB >> 2544305 |
E G Janzen1, L T Jandrisits, R V Shetty, D L Haire, J W Hilborn.
Abstract
General procedures for the synthesis and purification of 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) and its synthetic intermediates for electron paramagnetic resonance (EPR) spin trapping is described. The synthetic methods are not new per se and are based on Todd's original scheme (1959). In contrast to his account, however, we provide a detailed description of the numerous procedures and precautions necessary to obtain DMPO of very high 'chemical' and (most importantly) 'EPR' purity for use in biological spin trapping.Entities:
Mesh：
Substances：
Year: 1989 PMID： 2544305 DOI： 10.1016/0009-2797(89)90071-9
Source DB: PubMed Journal: Chem Biol Interact ISSN： 0009-2797 Impact factor: 5.192