Literature DB >> 2544250

Increased lipid peroxidation in malignant tissues of patients with colorectal cancer.

T Otamiri1, R Sjödahl.   

Abstract

The authors investigated the level of lipid peroxidation and possible related phenomena in the activation of phospholipase A2 and the infiltration of granulocyte neutrophils in human colorectal cancer tissue samples. Malondialdehyde (an index of lipid peroxidation), phospholipase A2 activity, and myeloperoxidase activity (a marker of granulocyte neutrophils) were found to be increased significantly in cancerous compared with macroscopically normal tissues. They concluded that increased lipid peroxidation, phospholipase A2, and myeloperoxidase activity are associated with human colorectal cancer.

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Year:  1989        PMID： 2544250     DOI： 10.1002/1097-0142(19890715)64:2<422::aid-cncr2820640214>3.0.co;2-2

Source DB:  PubMed          Journal:  Cancer        ISSN： 0008-543X            Impact factor:   6.860


  15 in total

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8.  High myeloperoxidase positive cell infiltration in colorectal cancer is an independent favorable prognostic factor.

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Review 9.  Reactive oxygen species and sperm cells.

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Review 10.  Oxidative Stress and Carbonyl Lesions in Ulcerative Colitis and Associated Colorectal Cancer.

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