Takanori Masuda1, Yoshinori Funama2, Naoyuki Imada3, Tomoyasu Sato4, Takuji Yamagami5, Fuminari Tatsugami5, Kazuo Awai5. 1. Department of Radiological Technology, Tsuchiya General Hospital, Nakajima-cho 3-30, Naka-ku, Hiroshima 730-8655, Japan; Department of Diagnostic Radiology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan. Electronic address: takanorimasuda@yahoo.co.jp. 2. Department of Medical Physics, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan. 3. Department of Radiological Technology, Tsuchiya General Hospital, Nakajima-cho 3-30, Naka-ku, Hiroshima 730-8655, Japan. 4. Department of Diagnostic Radiology, Tsuchiya General Hospital, Hiroshima Japan. 5. Department of Diagnostic Radiology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Abstract
RATIONALE AND OBJECTIVES: The purpose of our study was to compare test bolus techniques using undiluted or diluted contrast material for their ability to predict aortic enhancement on coronary computed tomographic angiography (c-CTA) images. MATERIALS AND METHODS: We divided 200 consecutive patients who underwent c-CTA on a 64-MDCT scanner into two groups. In group A (n = 100), we used a test bolus of undiluted contrast material and in group B (n = 100), the contrast material was diluted. The injection volume was body weight × 0.2 (contrast material 100%) in group A and body weight × 0.7 (contrast material 30%, saline 70%) in group B. We then compared the CT number in the ascending aorta on c-CTA images obtained with undiluted and diluted contrast media to the CT number on c-CTA images. RESULTS: The mean CT number in the ascending aorta was significantly higher in group B than group A (217.1 vs. 157.4 HU, P < .001). There was a significant difference in the correlation between the CT number of the ascending aorta on c-CTA images and on images acquired with the test bolus using undiluted or diluted test bolus (P < .001). In group B, the correlation had a strong positive linear relationship (r = 0.72, P < .001), whereas in group A the positive linear relationship was weak (r = 0.36). CONCLUSIONS: The test bolus with diluted contrast material was useful for predicting aortic enhancement before c-CTA scanning.
RATIONALE AND OBJECTIVES: The purpose of our study was to compare test bolus techniques using undiluted or diluted contrast material for their ability to predict aortic enhancement on coronary computed tomographic angiography (c-CTA) images. MATERIALS AND METHODS: We divided 200 consecutive patients who underwent c-CTA on a 64-MDCT scanner into two groups. In group A (n = 100), we used a test bolus of undiluted contrast material and in group B (n = 100), the contrast material was diluted. The injection volume was body weight × 0.2 (contrast material 100%) in group A and body weight × 0.7 (contrast material 30%, saline 70%) in group B. We then compared the CT number in the ascending aorta on c-CTA images obtained with undiluted and diluted contrast media to the CT number on c-CTA images. RESULTS: The mean CT number in the ascending aorta was significantly higher in group B than group A (217.1 vs. 157.4 HU, P < .001). There was a significant difference in the correlation between the CT number of the ascending aorta on c-CTA images and on images acquired with the test bolus using undiluted or diluted test bolus (P < .001). In group B, the correlation had a strong positive linear relationship (r = 0.72, P < .001), whereas in group A the positive linear relationship was weak (r = 0.36). CONCLUSIONS: The test bolus with diluted contrast material was useful for predicting aortic enhancement before c-CTA scanning.
Authors: Jack W Lambert; Yuxin Sun; Karen G Ordovas; Robert G Gould; Sizhe Wang; Benjamin M Yeh Journal: J Comput Assist Tomogr Date: 2018 May/Jun Impact factor: 1.826