Literature DB >> 25441628

Aging in the canine and feline brain.

Charles H Vite1, Elizabeth Head2.   

Abstract

Aging dogs and cats show neurodegenerative features that are similar to human aging and Alzheimer disease. Neuropathologic changes with age may be linked to signs of cognitive dysfunction both in the laboratory and in a clinic setting. Less is known about cat brain aging and cognition and this represents an area for further study. Neurodegenerative diseases such as lysosomal storage diseases in dogs and cats also show similar features of human aging, suggesting some common underlying pathogenic mechanisms and also suggesting pathways that can be modified to promote healthy brain aging.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cat; Cognitive dysfunction; Dog; Neuron loss; Tau; β-Amyloid

Mesh：

Year:  2014        PMID： 25441628      PMCID： PMC4254595          DOI： 10.1016/j.cvsm.2014.07.008

Source DB:  PubMed          Journal:  Vet Clin North Am Small Anim Pract        ISSN： 0195-5616            Impact factor:   2.093


  133 in total

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Authors:  M S Levine; R L Lloyd; R S Fisher; C D Hull; N A Buchwald
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Review 6.  Mechanism of cerebral beta-amyloid angiopathy: murine and cellular models.

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Review 7.  The canine (dog) model of human aging and disease: dietary, environmental and immunotherapy approaches.

Authors:  Carl W Cotman; Elizabeth Head
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8.  Postnatal development of inflammation in a murine model of Niemann-Pick type C disease: immunohistochemical observations of microglia and astroglia.

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Authors:  M J Russell; R White; E Patel; W R Markesbery; C R Watson; J W Geddes
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Review 2.  Can Animal Models Inform on the Relationship between Depression and Alzheimer Disease?

Authors:  Jennifer N K Nyarko; Maa O Quartey; Glen B Baker; Darrell D Mousseau
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Review 4.  The dog aging project: translational geroscience in companion animals.

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Journal:  Mamm Genome       Date:  2016-05-03       Impact factor: 2.957

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Review 7.  Translational models for vascular cognitive impairment: a review including larger species.

Authors:  Atticus H Hainsworth; Stuart M Allan; Johannes Boltze; Catriona Cunningham; Chad Farris; Elizabeth Head; Masafumi Ihara; Jeremy D Isaacs; Raj N Kalaria; Saskia A M J Lesnik Oberstein; Mark B Moss; Björn Nitzsche; Gary A Rosenberg; Julie W Rutten; Melita Salkovic-Petrisic; Aron M Troen
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8.  Network analysis of canine brain morphometry links tumour risk to oestrogen deficiency and accelerated brain ageing.

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9.  Multiple infarcts and hemorrhages in the central nervous system of a dog with cerebral amyloid angiopathy: a case report.

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10.  An inter-laboratory trial as a tool to increase rabies diagnostic capabilities of Sub-Saharan African Veterinary laboratories.

Authors:  Morgane Gourlaouen; Angélique Angot; Marzia Mancin; Charles Bebay; Baba Soumaré; Francesca Ellero; Barbara Zecchin; Stefania Leopardi; Cristian De Battisti; Calogero Terregino; Paola De Benedictis
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