Literature DB >> 25440915

Aciclovir-induced neurotoxicity: Utility of CSF and serum CMMG levels in diagnosis.

L Berry1, P Venkatesan2.   

Abstract

Aciclovir is an anti-viral frequently used for herpes virus infections. Neurotoxicity and nephrotoxicity are uncommon but serious side effects of aciclovir treatment. This case illustrates how aciclovir induced neurotoxicity can present and how it can be diagnosed using quantitative assays of aciclovir and its metabolite in the CSF and serum.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  9-Carboxymethoxymethylguanine; ACV; Aciclovir; CMMG; Neurotoxicity

Mesh：

Substances：

Year:  2014        PMID： 25440915     DOI： 10.1016/j.jcv.2014.09.001

Source DB:  PubMed          Journal:  J Clin Virol        ISSN： 1386-6532            Impact factor:   3.168


  5 in total

1.  Comparison of three cell-based drug screening platforms for HSV-1 infection.

Authors:  Leonardo D'Aiuto; Kelly Williamson; Peter Dimitrion; James McNulty; Carla E Brown; Chanti Babu Dokuburra; Alexander J Nielsen; Wen Jing Lin; Paolo Piazza; Mark E Schurdak; Joel Wood; Robert H Yolken; Paul R Kinchington; David C Bloom; Vishwajit L Nimgaonkar
Journal:  Antiviral Res       Date:  2017-03-23       Impact factor: 5.970

2.  Clinical study of Gene-Eden-VIR/Novirin in genital herpes: suppressive treatment safely decreases the duration of outbreaks in both severe and mild cases.

Authors:  Hanan Polansky; Edan Itzkovitz; Adrian Javaherian
Journal:  Clin Transl Med       Date:  2016-10-20

3.  Rapid determination of acyclovir, its main metabolite 9-carboxymethoxymethylguanine, ganciclovir, and penciclovir in human serum using LC-MS/MS.

Authors:  Andreas Ärlemalm; Anders Helldén; Louise Karlsson; Björn Carlsson
Journal:  Biomed Chromatogr       Date:  2022-01-28       Impact factor: 1.911

4.  Clinical study in genital herpes: natural Gene-Eden-VIR/Novirin versus acyclovir, valacyclovir, and famciclovir.

Authors:  Hanan Polansky; Adrian Javaherian; Edan Itzkovitz
Journal:  Drug Des Devel Ther       Date:  2016-08-29       Impact factor: 4.162

5.  Clinical Trial of Herbal Treatment Gene-Eden-VIR/Novirin in Oral Herpes.

Authors:  Hanan Polansky; Adrian Javaherian; Edan Itzkovitz
Journal:  J Evid Based Integr Med       Date:  2018 Jan-Dec
  5 in total

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