Literature DB >> 25440759

Electrosurgical management of Hunner ulcers in a referral center's interstitial cystitis population.

Avinash Chennamsetty1, Iyad Khourdaji2, Jonathan Goike3, Kim A Killinger2, Benjamin Girdler4, Kenneth M Peters5.   

Abstract

OBJECTIVE: To characterize electrocautery (EC) as a valid treatment option in interstitial cystitis (IC) patients with Hunner ulcers (HUs).
METHODS: From 1997 to 2013, a single urologist's IC population was retrospectively reviewed to identify HU patients as well as their demographics, operative characteristics, and response to a 2-page questionnaire evaluating parameters of their experience with EC. Descriptive statistics, Pearson chi-square test, Student t test, and Pearson coefficient were used.
RESULTS: Two hundred fourteen EC procedures were performed in 76 patients (87% women; mean age, 66 ± 1.67 years). Fifty-one patients (69%) who underwent multiple EC had mean initial bladder capacity of 438.62 ± 27.90 mL and final bladder capacity of 422.40 ± 30.10 mL. Mean number of EC procedures was 2.98 ± 0.25 (range, 1-11). Mean time between sessions was 14.52 ± 1.34 months (range, 1-121 months). Fifty-two patients (68%) completed our questionnaire, with 13.54 ± 1.28 years of symptoms and 10.66 ± 0.96 years since diagnosis. Ranking IC treatments, 37 patients (84%) reported EC most beneficial. On a 0-10 (none to worst possible) scale before and after EC, frequency improved from 9.04 ± 1.30 to 3.65 ± 2.75 (P <.001), urgency from 8.40 ± 2.38 to 3.28 ± 2.71 (P <.001), and pain from 8.62 ± 2.36 to 2.68 ± 2.55 (P <.001). Overall, 89.6% of patients noted some degree of symptom improvement after EC; 56.3% of patients had marked improvement. A total of 98% of patients would undergo EC again.
CONCLUSION: EC of HU is an effective and safe procedure with high patient satisfaction that does not diminish bladder capacity.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 25440759     DOI: 10.1016/j.urology.2014.09.012

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  15 in total

1.  Pain relief after triamcinolone infiltration in patients with bladder pain syndrome with Hunner's ulcers.

Authors:  Laura Mateu; Laura Izquierdo; Agustín Franco; Meritxell Costa; Nathan Lawrentschuk; Antonio Alcaraz
Journal:  Int Urogynecol J       Date:  2016-12-06       Impact factor: 2.894

2.  CUA guideline: Diagnosis and treatment of interstitial cystitis/bladder pain syndrome.

Authors:  Ashley Cox; Nicole Golda; Genevieve Nadeau; J Curtis Nickel; Lesley Carr; Jacques Corcos; Joel Teichman
Journal:  Can Urol Assoc J       Date:  2016-05-12       Impact factor: 1.862

Review 3.  [S2K guideline on the diagnosis and treatment of interstitial cystitis (IC/BPS) : Discussion of the current guideline using a case study].

Authors:  J Tolle; B T Kaftan; Th Bschleipfer
Journal:  Urologe A       Date:  2022-01-17       Impact factor: 0.639

4.  Ulcerative interstitial cystitis in an adolescent successfully treated with complete transurethral ulcer resection: A case report.

Authors:  Eri Yuki; Kenji Obara; Hiroo Kuroki; Hiroyuki Yamazaki; Kazutoshi Yamana; Akira Tadokoro; Kaede Hiruma; Yoshihiko Tomita
Journal:  IJU Case Rep       Date:  2018-12-14

Review 5.  Interstitial cystitis/bladder pain syndrome: The evolving landscape, animal models and future perspectives.

Authors:  Yoshiyuki Akiyama; Yi Luo; Philip M Hanno; Daichi Maeda; Yukio Homma
Journal:  Int J Urol       Date:  2020-04-04       Impact factor: 3.369

6.  Long-term outcomes of ulcerative interstitial cystitis after complete transurethral resection with therapeutic hydrodistention.

Authors:  Sang Wook Lee; Woong Bin Kim; Kwang Woo Lee; Jun Mo Kim; Jae Heon Kim; Ji Eun Moon; Si Hyun Kim; Young Ho Kim
Journal:  Int Urol Nephrol       Date:  2020-09-14       Impact factor: 2.370

7.  Peroxisome proliferator-activated receptor gamma agonist as a novel treatment for interstitial cystitis: A rat model.

Authors:  Amandeep Mahal; Nichole Young-Lin; Amy Dobberfuhl; Jaclyn Estes; Craig Vance Comiter
Journal:  Investig Clin Urol       Date:  2018-06-15

8.  Current best practice management of interstitial cystitis/bladder pain syndrome.

Authors:  Esther Han; Laura Nguyen; Larry Sirls; Kenneth Peters
Journal:  Ther Adv Urol       Date:  2018-03-19

Review 9.  From bladder to systemic syndrome: concept and treatment evolution of interstitial cystitis.

Authors:  Sara Dinis; Joana Tavares de Oliveira; Rui Pinto; Francisco Cruz; Ca Tony Buffington; Paulo Dinis
Journal:  Int J Womens Health       Date:  2015-07-23

Review 10.  A multidisciplinary approach to the evaluation and management of interstitial cystitis/bladder pain syndrome: an ideal model of care.

Authors:  Priyanka Gupta; Natalie Gaines; Larry T Sirls; Kenneth M Peters
Journal:  Transl Androl Urol       Date:  2015-12
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