Literature DB >> 25440594

Pleiotropic effects of statin in therapy in heart failure: a review.

Michele Correale, Silvia Abruzzese, Carmen A Greco, Morena Concilio, Matteo Di Biase, Natale D Brunetti1.   

Abstract

Clinical trials demonstrated that statin therapy is associated with a significant reduction in cardiovascular morbidity and mortality when used for either primary or secondary prevention of cardiovascular events. Several studies have shown that statins, having an important effect in the prevention of acute coronary syndromes, are also able to prevent heart failure (HF) in patients with coronary artery disease. This review summarizes the experimental and clinical evidence regarding the role of statins in the management of HF.

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Year:  2014        PMID： 25440594     DOI： 10.2174/1570161112999141127161508

Source DB:  PubMed          Journal:  Curr Vasc Pharmacol        ISSN： 1570-1611            Impact factor:   2.719


  4 in total

1.  The UPRmt Protects Caenorhabditis elegans from Mitochondrial Dysfunction by Upregulating Specific Enzymes of the Mevalonate Pathway.

Authors:  Olga Oks; Shany Lewin; Irina Langier Goncalves; Amir Sapir
Journal:  Genetics       Date:  2018-03-29       Impact factor: 4.562

2.  Response of the human myocardium to ischemic injury and preconditioning: The role of cardiac and comorbid conditions, medical treatment, and basal redox status.

Authors:  Kelly Casós; Gemma Ferrer-Curriu; Paula Soler-Ferrer; María L Pérez; Eduard Permanyer; Arnau Blasco-Lucas; Juan Manuel Gracia-Baena; Miguel A Castro; Carlos Sureda; Jordi Barquinero; Manuel Galiñanes
Journal:  PLoS One       Date:  2017-04-05       Impact factor: 3.240

3.  Simvastatin ameliorates ventricular remodeling via the TGF‑β1 signaling pathway in rats following myocardial infarction.

Authors:  Xiangbin Xiao; Guanglei Chang; Jian Liu; Guangyun Sun; Li Liu; Shu Qin; Dongying Zhang
Journal:  Mol Med Rep       Date:  2016-04-25       Impact factor: 2.952

4.  Synergistic effects of HMG-CoA reductase inhibitor and angiotensin II receptor blocker on load-induced heart failure.

Authors:  Yusuke Ito; Yasuhiro Maejima; Natsuko Tamura; Yuka Shiheido-Watanabe; Masanori Konishi; Takashi Ashikaga; Kenzo Hirao; Mitsuaki Isobe
Journal:  FEBS Open Bio       Date:  2018-04-10       Impact factor: 2.693
  4 in total

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